I. Summary

SecReT6 ID	322
Strain	Escherichia coli UMN026
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_011751
Location	243396..264517
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	2	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	ECUMN_0211 (rnhA)	238606..239073 [-], 468	218703463	ribonuclease H
2	ECUMN_0212 (dnaQ)	239138..239869 [+], 732	218703464	DNA polymerase III subunit epsilon
3	ECUMN_0213 (yafT)	240405..241190 [+], 786	218703465	putative aminopeptidase
4	ECUMN_0214	241530..242009 [-], 480	218703466	hypothetical protein	TssD
5	ECUMN_0215	242027..243526 [-], 1500	218703467	hypothetical protein	TssA
6	ECUMN_0216	243396..246923 [-], 3528	218703468	hypothetical protein	TssM
7	ECUMN_0217	246943..248451 [-], 1509	218703469	hypothetical protein	TssA
8	ECUMN_0218	248390..249133 [-], 744	218703470	hypothetical protein
9	ECUMN_0219	249130..251862 [-], 2733	218703471	putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity	TssH
10	ECUMN_0220	251872..252645 [-], 774	218703472	hypothetical protein	TssL
11	ECUMN_0221	252650..253996 [-], 1347	218703473	hypothetical protein	TssK
12	ECUMN_0222	253999..254523 [-], 525	218703474	hypothetical protein	TssJ
13	ECUMN_0223	254520..255908 [-], 1389	218703475	hypothetical protein	Fha
14	ECUMN_0224	255817..256866 [-], 1050	218703476	hypothetical protein	TssG
15	ECUMN_0225	256830..258689 [-], 1860	218703477	hypothetical protein	TssF
16	ECUMN_0226	258677..259102 [-], 426	218703478	hypothetical protein	TssE
17	ECUMN_0227	259107..260591 [-], 1485	218703479	hypothetical protein	TssC
18	ECUMN_0228	260614..261117 [-], 504	218703480	hypothetical protein	TssB
19	ECUMN_0229	261820..262338 [+], 519	218703481	hypothetical protein	TssD
20	ECUMN_0230	262559..264517 [+], 1959	218703482	putative VgrG/E protein	TssI
21	ECUMN_0231	264514..265356 [+], 843	218703483	hypothetical protein
22	ECUMN_0232	265378..266949 [+], 1572	218703484	hypothetical protein
23	ECUMN_0233	267016..268026 [+], 1011	218703485	hypothetical protein
24	ECUMN_0234 (yhhI)	268336..269295 [+], 960	218703486	putative transposase
25	ECUMN_0235	269323..269463 [-], 141	218703487	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA2866

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	ECUMN_0229	261820..262338 [+], 519	218703481	hypothetical protein	ECA2866

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Proteins        Genes

N/A

N/A