I. Summary
SecReT6 ID326 insolico
StrainPseudomonas aeruginosa LESB58
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PLES_365114041135..4041455 [+], 321218892369hypothetical protein 
2PLES_365214041512..4042069 [+], 558218892370hypothetical protein 
3PLES_36531 (folE)4042147..4042692 [+], 546218892371GTP cyclohydrolase I 
4PLES_365414042757..4043218 [-], 462218892372hypothetical protein 
5PLES_365514043464..4043844 [+], 381218892373putative enzyme 
6PLES_36561 (stk1)4043872..4044861 [-], 990218892374serine-threonine kinase Stk1  Stk1
7PLES_36571 (stp1)4044858..4045586 [-], 729218892375serine/threonine phosphoprotein phosphatase Stp1  Stp1
8PLES_365814045586..4049113 [-], 3528218892376hypothetical protein  TssM
9PLES_365914049129..4049998 [-], 870218892377putative outer membrane protein  TssL
10PLES_366014050001..4051332 [-], 1332218892378hypothetical protein  TssK
11PLES_366114051329..4051835 [-], 507218892379putative lipoprotein  TssJ
12PLES_366214051841..4053034 [-], 1194218892380hypothetical protein  Fha
13PLES_366314053052..4053192 [-], 141218892381hypothetical protein 
14PLES_366414053281..4054792 [-], 1512218892382putative transcriptional regulator  Sfa2
15PLES_366514054803..4057436 [-], 2634218892383putative ClpA/B-type protease  TssH
16PLES_366614057443..4058450 [-], 1008218892384hypothetical protein  TssG
17PLES_366714058414..4059994 [-], 1581218892385hypothetical protein  TssF
18PLES_366814060539..4060946 [-], 408218892386hypothetical protein  TssE
19PLES_366914060959..4062434 [-], 1476218892387hypothetical protein  TssC
20PLES_367014062463..4062969 [-], 507218892388hypothetical protein  TssB
21PLES_367114063005..4064561 [-], 1557218892389hypothetical protein  TssA
22PLES_367214065733..4066335 [-], 603218892390putative glutathione S-transferase 
23PLES_367314066391..4067557 [-], 1167218892391putative aminotransferase 
24PLES_367414067639..4068115 [+], 477218892392putative transcriptional regulator 
25PLES_367514068166..4068801 [-], 636218892393hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PSPTO_5435 , PSPTO_5435, PSPTO_5435

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PLES_02591(hcpC)289993..290511 [-], 519218889003secreted protein Hcp PSPTO_5435
2PLES_38981(hcpA)4308128..4308646 [+], 519218892612secreted protein Hcp PSPTO_5435
3PLES_56611(hcpB)6268805..6269323 [-], 519218894369secreted protein Hcp PSPTO_5435

Download FASTA format files
Proteins        Genes
(1) Barret M et al. (2011). Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered. Microbiology. 157(Pt 6):1726-39. [PudMed:21474537] in_silico
in_silico This literature contains bioinformatics investigation