I. Summary
SecReT6 ID330 insolico
StrainSalmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SPC_0270 (mltD)295946..297313 [-], 1368224582101membrane-bound lytic murein transglycosylase D 
2SPC_0271 (gloB)297385..298140 [-], 756224582102hydroxyacylglutathione hydrolase 
3SPC_0272 (yafS)298229..298897 [+], 669224582103hypothetical protein 
4SPC_0273 (rnhA)298894..299361 [-], 468224582104ribonuclease H 
5SPC_0274 (dnaQ)299416..300156 [+], 741224582105DNA polymerase III subunit epsilon 
6SPC_0275300684..301742 [-], 1059224582106cytoplasmic protein  TssA
7SPC_0276301753..302748 [-], 996224582107hypothetical protein  TssG
8SPC_0277302745..304628 [-], 1884224582108hypothetical protein  TssF
9SPC_0278304644..305138 [-], 495224582109hypothetical protein  TssE
10SPC_0279305135..305959 [-], 825224582110hypothetical protein  TagJ
11SPC_0280305946..306836 [-], 891224582111hypothetical protein 
12SPC_0282307216..309855 [+], 2640224582113ClpB-like protein  TssH
13SPC_0283309955..310497 [+], 543224582114hypothetical protein  TssB
14SPC_0284310521..312029 [+], 1509224582115cytoplasmic protein  TssC
15SPC_0285312303..312482 [+], 180224582116hypothetical protein 
16SPC_0286312660..312941 [+], 282224582117cytoplasmic protein 
17SPC_0287313193..313678 [+], 486224582118hypothetical protein  TssD
18SPC_0288313790..314281 [+], 492224582119lipoprotein  TssJ
19SPC_0289314285..315628 [+], 1344224582120hypothetical protein  TssK
20SPC_0290315625..316929 [+], 1305224582121hypothetical protein  TssL
21SPC_0291316934..317707 [+], 774224582122hypothetical protein 
22SPC_0292318119..318340 [+], 222224582123shiga-like toxin A subunit 
23SPC_0293318373..321999 [+], 3627224582124hypothetical protein  TssM
24SPC_0294322032..322787 [+], 756224582125hypothetical protein 
25SPC_0295322784..323200 [+], 417224582126hypothetical protein 
26SPC_0296323224..323745 [+], 522224582127cytoplasmic protein 
27SPC_0297323886..324095 [+], 210224582128hypothetical protein 
28SPC_0298324141..326375 [+], 2235224582129Rhs family protein  TssI
29SPC_0299326435..326893 [+], 459224582130hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STY2606, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SPC_0287313193..313678 [+], 486224582118hypothetical protein SciK
2SPC_13301392931..1393332 [-], 402224583136hypothetical protein STY2606
3SPC_31983228676..3229161 [-], 486224584925hypothetical protein Hcp

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Proteins        Genes

Homology Immunity protein list

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SPC_13291392413..1392931 [-], 519224583135lipoprotein STY2607

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Proteins        Genes
(1) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904] in_silico
in_silico This literature contains bioinformatics investigation