I. Summary
SecReT6 ID336 insolico
StrainVibrio cholerae MJ-1236
Repliconchromosome 2 [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1VCD_000116127946..128830 [-], 885229605176D-ribose transporter subunit RbsB 
2VCD_000117 (rbsC)128885..129886 [-], 1002229605177ribose ABC transporter permease protein 
3VCD_000118129883..131385 [-], 1503229605178D-ribose transporter ATP binding protein 
4VCD_000119131412..131882 [-], 471229605179D-ribose pyranase 
5VCD_000120131883..132014 [+], 132229605180hypothetical protein 
6VCD_000121132115..132375 [+], 261229605181hypothetical protein 
7VCD_000122132888..135941 [-], 3054229605182VgrG protein  TssI
8VCD_000123136194..137459 [-], 1266229605183type VI secretion-related protein VasL  TssA
9VCD_000124137507..141052 [-], 3546229605184IcmF-related protein  TssM
10VCD_000125141068..142477 [-], 1410229605185hypothetical protein  TssA
11VCD_000126142487..143170 [-], 684229605186type VI secretion protein VasI  VCA0118
12VCD_000127143140..144732 [-], 1593229605187sigma-54 dependent transcriptional regulator  VasH
13VCD_000128144735..147344 [-], 2610229605188ClpB protein  TssH
14VCD_000129147370..148143 [-], 774229605189ImpK/VasF outer membrane protein  TssL
15VCD_000130148146..149480 [-], 1335229605190hypothetical protein  TssK
16VCD_000131149487..149963 [-], 477229605191type VI secretion lipoprotein/VasD  TssJ
17VCD_000132149966..151453 [-], 1488229605192hypothetical protein  Fha
18VCD_000133151456..152472 [-], 1017229605193hypothetical protein  TssG
19VCD_000134152436..154205 [-], 1770229605194protein ImpG/VasA  TssF
20VCD_000135154211..154648 [-], 438229605195hypothetical protein  TssE
21VCD_000136154651..156129 [-], 1479229605196hypothetical protein  TssC
22VCD_000137156170..156676 [-], 507229605197hypothetical protein  TssB
23VCD_000138157108..158103 [-], 996229605198hypothetical protein 
24VCD_000139158096..158380 [-], 285229605199uropathogenic specific protein  PAAR
25VCD_000140159119..160831 [+], 1713229605200pseudouridylate synthase LSU rRNA-specific 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
VCA0123 , VCA0118, VCA0020, VCA0018, VCA0017, VCA0285, VC1418, VC1416, ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1VCD_000122132888..135941 [-], 3054229605182VgrG protein VCA0123
2VCD_000126142487..143170 [-], 684229605186type VI secretion protein VasI VCA0118
3VCD_000213246869..250126 [-], 3258229605273hypothetical protein VCA0020
4VCD_000215251010..253094 [-], 2085229605275VgrG protein VCA0018
5VCD_000216253222..253740 [-], 519229605276Hcp protein VCA0017
6VCD_0009891054475..1055146 [-], 672229606039hypothetical protein VCA0285
7VCD_0029292127535..2129460 [-], 1926229608011lipase family protein VC1418
8VCD_0029312130302..2133793 [-], 3492229608013VgrG protein VC1416
9VCD_0029322133921..2134439 [-], 519229608014Hcp protein ABG57132

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Homology Immunity protein list
VCA0021, VC1419

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1VCD_000212246140..246868 [-], 729229605272hypothetical protein VCA0021
2VCD_0029282126795..2127538 [-], 744229608010hypothetical protein VC1419

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Proteins        Genes