I. Summary

SecReT6 ID	345
Strain	Klebsiella pneumoniae NTUH-K2044
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_012731
Location	3190436..3214872
Comment
Function	N/A
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	0	0	1	1	1	0	0	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	KP1_3358	3186554..3186829 [-], 276	238895302	hypothetical protein
2	KP1_3359 (pth)	3187102..3187686 [+], 585	238895303	peptidyl-tRNA hydrolase
3	KP1_3361 (ychF)	3187804..3188895 [+], 1092	238895304	GTP-dependent nucleic acid-binding protein EngD
4	KP1_3362	3188977..3189306 [-], 330	238895305	hypothetical protein
5	KP1_3363 (mocB)	3189390..3190304 [-], 915	238895306	putative rhizopine uptake ABC transport system periplasmic solute-binding protein precursor
6	KP1_3364	3190436..3191893 [-], 1458	238895307	hypothetical protein	TssA
7	KP1_3366	3191871..3192320 [-], 450	238895308	hypothetical protein	TssE
8	KP1_3367	3192317..3192859 [-], 543	238895309	hypothetical protein	TssJ
9	KP1_3368	3192834..3193880 [-], 1047	238895310	hypothetical protein	TssG
10	KP1_3369	3193880..3195643 [-], 1764	238895311	hypothetical protein	TssF
11	KP1_3370	3195777..3199193 [-], 3417	238895312	hypothetical protein	TssM
12	KP1_3371	3199171..3200328 [-], 1158	238895313	hypothetical protein
13	KP1_3372	3200332..3200598 [-], 267	238895314	hypothetical protein	PAAR
14	KP1_3373	3200877..3201155 [-], 279	238895315	hypothetical protein
15	KP1_3374	3201166..3201324 [-], 159	238895316	hypothetical protein
16	KP1_3375	3201344..3201583 [-], 240	238895317	hypothetical protein
17	KP1_3376	3201587..3201703 [-], 117	238895318	hypothetical protein
18	KP1_3378	3201821..3202714 [-], 894	238895319	hypothetical protein
19	KP1_3379	3202898..3203791 [-], 894	238895320	sulfatase modifying factor 1 precursor-like protein
20	KP1_3380	3203967..3204860 [-], 894	238895321	hypothetical protein
21	KP1_3381	3205044..3205934 [-], 891	238895322	sulfatase modifying factor 1 precursor-like protein
22	KP1_3382	3205956..3208217 [-], 2262	238895323	hypothetical protein
23	KP1_3383	3208236..3210722 [-], 2487	238895324	hypothetical protein	TssI
24	KP1_3384	3210902..3211063 [-], 162	238895325	hypothetical protein
25	KP1_3385	3211181..3212878 [-], 1698	238895326	hypothetical protein	TagL
26	KP1_3386	3212882..3213535 [-], 654	238895327	hypothetical protein	TssL
27	KP1_3387	3213532..3214872 [-], 1341	238895328	hypothetical protein	TssK
28	KP1_3388	3215110..3215355 [-], 246	238895329	hypothetical protein
29	KP1_3389	3215442..3215771 [+], 330	238895330	hypothetical protein
30	KP1_3390	3215793..3216425 [+], 633	238895331	putative nucleoprotein/polynucleotide- associated enzyme
31	KP1_3392	3216451..3217149 [-], 699	238895332	putative ribosomal large subunit pseudouridine synthase A
32	KP1_3393	3217340..3217822 [+], 483	238895333	cold shock protein E
33	KP1_3394	3217932..3218831 [+], 900	238895334	LysR family transcriptional regulator
34	KP1_3395	3218806..3219615 [-], 810	238895335	extracellular solute-binding protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

N/A

N/A

(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940]

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