I. Summary
SecReT6 ID345 insolico
StrainKlebsiella pneumoniae NTUH-K2044
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1KP1_33583186554..3186829 [-], 276238895302hypothetical protein 
2KP1_3359 (pth)3187102..3187686 [+], 585238895303peptidyl-tRNA hydrolase 
3KP1_3361 (ychF)3187804..3188895 [+], 1092238895304GTP-dependent nucleic acid-binding protein EngD 
4KP1_33623188977..3189306 [-], 330238895305hypothetical protein 
5KP1_3363 (mocB)3189390..3190304 [-], 915238895306putative rhizopine uptake ABC transport system periplasmic solute-binding protein precursor 
6KP1_33643190436..3191893 [-], 1458238895307hypothetical protein  TssA
7KP1_33663191871..3192320 [-], 450238895308hypothetical protein  TssE
8KP1_33673192317..3192859 [-], 543238895309hypothetical protein  TssJ
9KP1_33683192834..3193880 [-], 1047238895310hypothetical protein  TssG
10KP1_33693193880..3195643 [-], 1764238895311hypothetical protein  TssF
11KP1_33703195777..3199193 [-], 3417238895312hypothetical protein  TssM
12KP1_33713199171..3200328 [-], 1158238895313hypothetical protein 
13KP1_33723200332..3200598 [-], 267238895314hypothetical protein  PAAR
14KP1_33733200877..3201155 [-], 279238895315hypothetical protein 
15KP1_33743201166..3201324 [-], 159238895316hypothetical protein 
16KP1_33753201344..3201583 [-], 240238895317hypothetical protein 
17KP1_33763201587..3201703 [-], 117238895318hypothetical protein 
18KP1_33783201821..3202714 [-], 894238895319hypothetical protein 
19KP1_33793202898..3203791 [-], 894238895320sulfatase modifying factor 1 precursor-like protein 
20KP1_33803203967..3204860 [-], 894238895321hypothetical protein 
21KP1_33813205044..3205934 [-], 891238895322sulfatase modifying factor 1 precursor-like protein 
22KP1_33823205956..3208217 [-], 2262238895323hypothetical protein 
23KP1_33833208236..3210722 [-], 2487238895324hypothetical protein  TssI
24KP1_33843210902..3211063 [-], 162238895325hypothetical protein 
25KP1_33853211181..3212878 [-], 1698238895326hypothetical protein  TagL
26KP1_33863212882..3213535 [-], 654238895327hypothetical protein  TssL
27KP1_33873213532..3214872 [-], 1341238895328hypothetical protein  TssK
28KP1_33883215110..3215355 [-], 246238895329hypothetical protein 
29KP1_33893215442..3215771 [+], 330238895330hypothetical protein 
30KP1_33903215793..3216425 [+], 633238895331putative nucleoprotein/polynucleotide- associated enzyme 
31KP1_33923216451..3217149 [-], 699238895332putative ribosomal large subunit pseudouridine synthase A 
32KP1_33933217340..3217822 [+], 483238895333cold shock protein E 
33KP1_33943217932..3218831 [+], 900238895334LysR family transcriptional regulator 
34KP1_33953218806..3219615 [-], 810238895335extracellular solute-binding protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation