I. Summary
SecReT6 ID349 insolico
StrainRalstonia pickettii 12D
Repliconchromosome I [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Rpic12D_16661769778..1770170 [+], 393241663261hypothetical protein 
2Rpic12D_16671770177..1771589 [+], 1413241663262FAD linked oxidase domain-containing protein 
3Rpic12D_16681771607..1771810 [-], 204241663263hypothetical protein 
4Rpic12D_16691772183..1772380 [+], 198241663264hypothetical protein 
5Rpic12D_16701772837..1773679 [-], 843241663265hypothetical protein 
6Rpic12D_16711773666..1773965 [-], 300241663266hypothetical protein 
7Rpic12D_16721774621..1775916 [-], 1296241663267OmpA/MotB domain-containing protein  TagL
8Rpic12D_16731775916..1779722 [-], 3807241663268type VI secretion protein IcmF  TssM
9Rpic12D_16741779735..1780982 [-], 1248241663269type VI secretion system OmpA/MotB family protein  TssL
10Rpic12D_16751781021..1782364 [-], 1344241663270type VI secretion protein  TssK
11Rpic12D_16761782373..1782891 [-], 519241663271type VI secretion lipoprotein  TssJ
12Rpic12D_16771782894..1783169 [-], 276241663272PAAR repeat-containing protein  PAAR
13Rpic12D_16781783321..1783587 [-], 267241663273hypothetical protein 
14Rpic12D_16791783898..1787044 [-], 3147241663274ImpA family type VI secretion-associated protein  TssI
15Rpic12D_16801787178..1787822 [-], 645241663275hypothetical protein 
16Rpic12D_16811787905..1788390 [-], 486241663276type VI secretion system effector  TssD
17Rpic12D_16821788527..1790020 [-], 1494241663277EvpB type VI secretion protein  TssC
18Rpic12D_16831790070..1790609 [-], 540241663278type VI secretion protein  TssB
19Rpic12D_16841790661..1793357 [-], 2697241663279type VI secretion ATPase, ClpV1 family  TssH
20Rpic12D_16851793799..1794401 [+], 603241663280hypothetical protein 
21Rpic12D_16861794391..1795218 [+], 828241663281virulence protein SciE type  TagJ
22Rpic12D_16871795420..1797642 [+], 2223241663282ribonuclease G and E 
23Rpic12D_16881797647..1799224 [+], 1578241663283hypothetical protein 
24Rpic12D_16891799230..1799751 [+], 522241663284type VI secretion system lysozyme-like protein  TssE
25Rpic12D_16901799756..1801636 [+], 1881241663285type VI secretion protein  TssF
26Rpic12D_16911801639..1802679 [+], 1041241663286type VI secretion protein  TssG
27Rpic12D_16921802666..1803748 [+], 1083241663287type VI secretion-associated protein, ImpA family  TssA
28Rpic12D_16931803829..1804104 [+], 276241663288response regulator receiver protein 
29Rpic12D_16941804157..1804627 [-], 471241663289AsnC family transcriptional regulator 
30Rpic12D_16951804773..1806251 [+], 1479241663290class V aminotransferase 
31Rpic12D_16961806270..1806791 [-], 522241663291AsnC family transcriptional regulator 
32Rpic12D_16971806937..1807953 [+], 10172416632921-aminocyclopropane-1-carboxylate deaminase 
33Rpic12D_16981808261..1808680 [+], 420241663293lipoprotein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
ROD_27741 , Rpic12D_3260

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Rpic12D_16811787905..1788390 [-], 486241663276type VI secretion system effector ROD_27741
2Rpic12D_32603440567..3440926 [+], 360241664838hypothetical protein Rpic12D_3260

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Proteins        Genes

Homology Immunity protein list

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Rpic12D_32613440936..3441391 [+], 456241664839hypothetical protein Rpic12D_3261

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Proteins        Genes
(1) Dong C et al. (2013). Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3. Biochem J. 454(1):59-68. [PudMed:23730712] experimental in_silico
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation