I. Summary
SecReT6 ID352 insolico
StrainAggregatibacter aphrophilus NJ8700
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1NT05HA_18481833338..1834063 [-], 726251793533PnuC transporter 
2NT05HA_18491834225..1837083 [+], 2859251793534RNA polymerase-associated protein RapA 
3NT05HA_18501837086..1837745 [+], 660251793535ribosomal large subunit pseudouridine synthase A 
4NT05HA_18511837937..1838434 [+], 498251793536type VI secretion protein  TssB
5NT05HA_18521838456..1839940 [+], 1485251793537type VI secretion protein, EvpB/family  TssC
6NT05HA_18531839950..1840366 [+], 417251793538type VI secretion system lysozyme-like protein  TssE
7NT05HA_18541840367..1842118 [+], 1752251793539type VI secretion protein  TssF
8NT05HA_18551842082..1843080 [+], 999251793540type VI secretion protein  TssG
9NT05HA_18561843082..1843867 [+], 786251793541hypothetical protein  Fha
10NT05HA_18571843882..1844568 [+], 687251793542type VI secretion lipoprotein, family  TssJ
11NT05HA_18581844572..1845915 [+], 1344251793543type VI secretion protein  TssK
12NT05HA_18591845912..1846769 [+], 858251793544VasF  TssL
13NT05HA_18601846795..1847421 [+], 627251793545hypothetical protein 
14NT05HA_18611847423..1848850 [+], 1428251793546hypothetical protein 
15NT05HA_18621849033..1852530 [+], 3498251793547type VI secretion protein IcmF  TssM
16NT05HA_18631852725..1852856 [-], 132251793548hypothetical protein 
17NT05HA_18641853020..1856250 [+], 3231251793549outer membrane autotransporter barrel 
18NT05HA_1865 (ribB)1856357..1857001 [-], 6452517935503,4-dihydroxy-2-butanone 4-phosphate synthase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NT05HA_18201811033..1811548 [+], 516251793505hemolysin co-regulated protein ECA2866

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Proteins        Genes
(1) Di Bonaventura MP et al. (2009). Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700. J Bacteriol. 191(14):4693-4. [PudMed:19447908] in_silico
in_silico This literature contains bioinformatics investigation