I. Summary
SecReT6 ID360 insolico
StrainEscherichia coli O157:H7 str. TW14359
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECSP_0213 (rnhA)239068..239535 [-], 468254791341ribonuclease H 
2ECSP_0214 (dnaQ)239600..240331 [+], 732254791342DNA polymerase III subunit epsilon 
3ECSP_0216 (yafT)240869..241669 [+], 801254791343aminopeptidase 
4ECSP_0217241854..242150 [-], 297254791344hypothetical protein 
5ECSP_0218242147..242602 [-], 456254791345hypothetical protein 
6ECSP_0219242599..243195 [-], 597254791346hypothetical protein 
7ECSP_0220243305..243496 [-], 192254791347hypothetical protein 
8ECSP_0221243517..243996 [-], 480254791348hypothetical protein  TssD
9ECSP_0222243962..245461 [-], 1500254791349hypothetical protein  TssA
10ECSP_0223245382..248816 [-], 3435254791350macrophage toxin  TssM
11ECSP_0224248953..250365 [-], 1413254791351ImpA domain-containing protein  TssA
12ECSP_0225250370..251113 [-], 744254791352hypothetical protein 
13ECSP_0226 (clpV)251110..253887 [-], 2778254791353Hsp100/Clp ATPase  TssH
14ECSP_0227253896..254657 [-], 762254791354hypothetical protein  TssL
15ECSP_0228254662..255993 [-], 1332254791355hypothetical protein  TssK
16ECSP_0229255996..256520 [-], 525254791356hypothetical protein  TssJ
17ECSP_0230256517..257818 [-], 1302254791357hypothetical protein  Fha
18ECSP_0231257822..258904 [-], 1083254791358hypothetical protein  TssG
19ECSP_0232258868..260718 [-], 1851254791359hypothetical protein  TssF
20ECSP_0233260722..261135 [-], 414254791360hypothetical protein  TssE
21ECSP_0234261226..262617 [-], 1392254791361hypothetical protein  TssC
22ECSP_0235262668..262892 [-], 225254791362hypothetical protein  TssC
23ECSP_0236262927..263427 [-], 501254791363hypothetical protein  TssB
24ECSP_0237263854..263997 [+], 144254791364hypothetical protein 
25ECSP_0238264124..264642 [+], 519254791365hypothetical protein  TssD
26ECSP_0239264675..264812 [+], 138254791366hypothetical protein 
27ECSP_0240264852..266993 [+], 2142254791367hypothetical protein  TssI
28ECSP_0241267069..271301 [+], 4233254791368hypothetical protein  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECSP_0238264124..264642 [+], 519254791365hypothetical protein ECA4275

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Proteins        Genes