I. Summary

SecReT6 ID	365
Strain	Escherichia coli O103:H2 str. 12009
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_013353
Location	240442..263882
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	2	1	1	2	1	2	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	ECO103_0207 (yafS)	235550..236272 [+], 723	260842439	S-adenosyl-L-methionine-dependent methyltransferase
2	ECO103_0208 (rnhA)	236269..236736 [-], 468	260842440	ribonuclease HI
3	ECO103_0209 (dnaQ)	236801..237532 [+], 732	260842441	DNA polymerase III, epsilon subunit DnaQ
4	ECO103_0210 (yafT)	238073..238858 [+], 786	260842442	aminopeptidase
5	ECO103_0211 (ykfM)	238995..239474 [-], 480	260842443	hypothetical protein
6	ECO103_0212	239484..240398 [-], 915	260842444	hypothetical protein
7	ECO103_0213	240442..240924 [-], 483	260842445	Hcp-like protein	TssD
8	ECO103_0214	240948..242300 [-], 1353	260842446	hypothetical protein	TssA
9	ECO103_0215	242311..245835 [-], 3525	260842447	IcmF-like protein	TssM
10	ECO103_0216	245854..247266 [-], 1413	260842448	hypothetical protein	TssA
11	ECO103_0217	247271..248014 [-], 744	260842449	hypothetical protein
12	ECO103_0218	248011..250776 [-], 2766	260842450	ATP-dependent Clp proteinase ATP-binding chain	TssH
13	ECO103_0219	250785..251546 [-], 762	260842451	hypothetical protein	TssL
14	ECO103_0220	251551..252882 [-], 1332	260842452	hypothetical protein	TssK
15	ECO103_0221	252885..253409 [-], 525	260842453	lipoprotein	TssJ
16	ECO103_0222	253406..254686 [-], 1281	260842454	hypothetical protein	Fha
17	ECO103_0223	254711..255793 [-], 1083	260842455	hypothetical protein	TssG
18	ECO103_0224	255757..257607 [-], 1851	260842456	hypothetical protein	TssF
19	ECO103_0225	257611..258024 [-], 414	260842457	hypothetical protein	TssE
20	ECO103_0226	258031..259506 [-], 1476	260842458	hypothetical protein	TssC
21	ECO103_0227	259557..259781 [-], 225	260842459	hypothetical protein	TssC
22	ECO103_0228	259816..260316 [-], 501	260842460	hypothetical protein	TssB
23	ECO103_0229	261013..261531 [+], 519	260842461	Hcp-like protein	TssD
24	ECO103_0230	261741..263882 [+], 2142	260842462	VgrG protein	TssI
25	ECO103_0231	263958..268205 [+], 4248	260842463	fused RhsG core protein with extension/ RhsI core protein	PAAR
26	ECO103_0232	268189..268671 [+], 483	260842464	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA4275

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	ECO103_0229	261013..261531 [+], 519	260842461	Hcp-like protein	ECA4275

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Proteins        Genes

N/A

N/A