I. Summary

SecReT6 ID	367
Strain	Escherichia coli O111:H- str. 11128
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_013364
Location	241320..264830
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	2	1	1	2	1	2	1	1
Component	TssG	TssJ	TssK	TssM
Number	0	1	1	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	ECO111_0210 (yafS)	236476..237198 [+], 723	260866356	putative S-adenosyl-L-methionine-dependent methyltransferase
2	ECO111_0211 (rnhA)	237195..237662 [-], 468	260866357	ribonuclease HI
3	ECO111_0212 (dnaQ)	237727..238458 [+], 732	260866358	DNA polymerase III subunit epsilon
4	ECO111_0215 (ykfM)	239873..240352 [-], 480	260866359	hypothetical protein
5	ECO111_0216	240362..241276 [-], 915	260866360	hypothetical protein
6	ECO111_0217	241320..241802 [-], 483	260866361	Hcp-like protein	TssD
7	ECO111_0218	241826..243178 [-], 1353	260866362	hypothetical protein	TssA
8	ECO111_0221	246731..248143 [-], 1413	260866363	hypothetical protein	TssA
9	ECO111_0222	248148..248891 [-], 744	260866364	hypothetical protein
10	ECO111_0223	248888..251725 [-], 2838	260866365	putative ATP-dependent Clp proteinase ATP-binding chain	TssH
11	ECO111_0224	251734..252495 [-], 762	260866366	hypothetical protein	TssL
12	ECO111_0225	252500..253831 [-], 1332	260866367	hypothetical protein	TssK
13	ECO111_0226	253834..254358 [-], 525	260866368	putative lipoprotein	TssJ
14	ECO111_0227	254355..255635 [-], 1281	260866369	hypothetical protein	Fha
15	ECO111_0230	256705..258555 [-], 1851	260866370	hypothetical protein	TssF
16	ECO111_0231	258559..258972 [-], 414	260866371	hypothetical protein	TssE
17	ECO111_0232	258979..260454 [-], 1476	260866372	hypothetical protein	TssC
18	ECO111_0233	260505..260729 [-], 225	260866373	hypothetical protein	TssC
19	ECO111_0234	260764..261264 [-], 501	260866374	hypothetical protein	TssB
20	ECO111_0235	261961..262479 [+], 519	260866375	Hcp-like protein	TssD
21	ECO111_0236	262689..264830 [+], 2142	260866376	VgrG protein	TssI
22	ECO111_0237	264906..269135 [+], 4230	260866377	fused putative RhsG core protein with extension/putative RhsI core protein	PAAR
23	ECO111_0238	269119..269601 [+], 483	260866378	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA4275

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	ECO111_0235	261961..262479 [+], 519	260866375	Hcp-like protein	ECA4275

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Proteins        Genes

N/A

N/A