SecReT6
I. Summary
SecReT6 ID374 insolico
StrainCitrobacter rodentium ICC168
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_013716
Location2914927..2946102
Comment
FunctionN/A
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1110
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ROD_276112910115..2910441 [+], 327283786427hypothetical protein 
2ROD_276212910455..2911294 [+], 840283786428hypothetical protein 
3ROD_276312911789..2914698 [-], 2910283786429outer membrane autotransporter 
4ROD_27641 (cts1D)2914927..2915430 [-], 504283786430T6SS lysozyme-related protein Cts1D  TssE
5ROD_27651 (cts1E)2915417..2916214 [-], 798283786431ImpE family T6SS protein Cts1E  TagJ
6ROD_27661 (cts1F)2916232..2917095 [-], 864283786432T6SS protein Cts1F  Fha
7ROD_27671 (cts1G)2917403..2919745 [-], 2343283786433VgrG family T6SS protein Cts1G  TssI
8ROD_27681 (cts1T)2919750..2920403 [-], 654283786434T6SS protein Cts1T 
9ROD_27711 (cts1U)2924258..2925613 [-], 1356283786435T6SS protein Cts1U  TssL
10ROD_27721 (cts1M)2925613..2926959 [-], 1347283786436T6SS protein Cts1M  TssK
11ROD_27731 (cts1N)2926963..2927490 [-], 528283786437T6SS protein Cts1N  TssJ
12ROD_27741 (cts1H)2927581..2928066 [-], 486283786438Hcp family T6SS protein Cts1H  TssD
13ROD_27751 (cts1B)2928226..2929725 [-], 1500283786439T6SS protein Cts1B  TssC
14ROD_27761 (cts1S)2929747..2930265 [-], 519283786440T6SS protein Cts1S  TssB
15ROD_277712930356..2930904 [-], 549283786441fimbrial adhesin 
16ROD_277812930895..2933438 [-], 2544283786442fimbrial usher protein 
17ROD_277912933529..2934284 [-], 756283786443fimbrial chaperone protein 
18ROD_278012934370..2934909 [-], 540283786444fimbrial subunit 
19ROD_27811 (cts1V)2934994..2937696 [-], 2703283786445T6SS protein Cts1V  TssH
20ROD_27821 (cts1C)2937987..2939867 [+], 1881283786446T6SS protein Cts1C  TssF
21ROD_27831 (cts1R)2939864..2940895 [+], 1032283786447T6SS protein Cts1R  TssG
22ROD_27841 (cts1A)2940892..2941962 [+], 1071283786448T6SS protein Cts1A  TssA
23ROD_278512941966..2942952 [+], 987283786449hypothetical protein 
24ROD_278612942978..2944324 [+], 1347283786450hypothetical protein 
25ROD_27871 (cts1O)2944318..2946102 [+], 1785283786451T6SS protein Cts1O  TagL
26ROD_27881 (cts1W)2946128..2946616 [+], 489283786452T6SS protein Cts1W 
27ROD_278912946669..2947391 [-], 723283786453ATP-binding protein of ABC transporter 
28ROD_279012947378..2948142 [-], 765283786454membrane component of ABC transporter 
29ROD_279112948206..2948973 [-], 768283786455ABC transporter substrate-binding protein 
30ROD_27921 (lpxP)2949778..2950698 [+], 921283786456palmitoleoyl acyltransferase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ROD_27741

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ROD_27741(cts1H)2927581..2928066 [-], 486283786438Hcp family T6SS protein Cts1H ROD_27741

Download FASTA format files
Proteins        Genes
N/A
(1) Gueguen E et al. (2014). Transcriptional Frameshifting Rescues Citrobacter rodentium Type VI Secretion by the Production of Two Length Variants from the Prematurely Interrupted tssM Gene. PLoS Genet. 10(12):e1004869. [PudMed:25474156] experimental
(2) Gueguen E et al. (2012). Promoter swapping unveils the role of the Citrobacter rodentium CTS1 Type VI secretion system in inter-bacterial competition. Appl Environ Microbiol. 79(1):32-8. [PudMed:23064344] experimental
 
experimental This literature contains experimental investigation