I. Summary
SecReT6 ID375 insolico
StrainCitrobacter rodentium ICC168
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i4a
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ROD_340513587374..3588120 [-], 747283787003DNA methyltransferase 
2ROD_340613588120..3589010 [-], 891283787004DNA methyltransferase 
3ROD_340713589021..3589278 [-], 258283787005hypothetical protein 
4ROD_340813589657..3589923 [+], 267283787006hypothetical protein 
5ROD_340913590040..3590510 [+], 471283787007heat shock protein 
6ROD_341013590565..3590957 [-], 393283787008hypothetical protein 
7ROD_34111 (cts2A)3590954..3591874 [-], 921283787009T6SS protein Cts2A  TssA
8ROD_34141 (cts2U)3595417..3596163 [-], 747283787010T6SS protein Cts2U  TssL
9ROD_34151 (cts2M)3596147..3597481 [-], 1335283787011T6SS protein Cts2M  TssK
10ROD_34161 (cts2N)3597483..3597953 [-], 471283787012T6SS protein Cts2N 
11ROD_34171 (cts2S)3598320..3598832 [+], 513283787013T6SS protein Cts2S  TssB
12ROD_34181 (cts2B)3598851..3600332 [+], 1482283787014T6SS protein Cts2B  TssC
13ROD_34191 (cts2H)3600351..3600836 [+], 486283787015Hcp family T6SS protein Cts2H  TssD
14ROD_34201 (ctsD)3600836..3601216 [+], 381283787016T6SS protein Cts2D  TssE
15ROD_34211 (cts2C)3601236..3602957 [+], 1722283787017T6SS protein Cts2C  TssF
16ROD_34221 (cts2R)3602921..3603856 [+], 936283787018T6SS protein Cts2R  TssG
17ROD_34231 (cts2V)3603847..3606354 [+], 2508283787019T6SS protein Cts2V  TssH
18ROD_34241 (cts2G)3606559..3608523 [+], 1965283787020VgrG family T6SS protein Cts2G  TssI
19ROD_342513608531..3609055 [+], 525283787021hypothetical protein 
20ROD_342613609279..3611639 [+], 2361283787022type I restriction-modification system, methylase (M) subunit 
21ROD_342713611639..3612979 [+], 1341283787023type I restriction-modification system, specificity (S) subunit 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
Hcp , Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ROD_34191(cts2H)3600351..3600836 [+], 486283787015Hcp family T6SS protein Cts2H Hcp
2ROD_38091(ctsH1)4016006..4016491 [+], 486283787382Hcp family T6SS protein CtsH1 Hcp

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Proteins        Genes