I. Summary
SecReT6 ID377 insolico
StrainKlebsiella variicola At-22
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Kvar_29483070204..3070410 [+], 207288935807hypothetical protein 
2Kvar_29493070460..3071338 [-], 879288935808AraC family transcriptional regulator 
3Kvar_29503071497..3072252 [+], 756288935809short-chain dehydrogenase/reductase SDR 
4Kvar_29513072257..3072850 [-], 594288935810TetR family transcriptional regulator 
5Kvar_29523072924..3073637 [+], 714288935811short-chain dehydrogenase/reductase SDR 
6Kvar_29533073704..3074198 [-], 495288935812hypothetical protein 
7Kvar_29543074324..3074866 [-], 543288935813type VI secretion lipoprotein  TssJ
8Kvar_29553074844..3075929 [-], 1086288935814type VI secretion protein  TssG
9Kvar_29563075893..3077647 [-], 1755288935815type VI secretion protein  TssF
10Kvar_29573077727..3079319 [-], 1593288935816type VI secretion-associated protein  TssA
11Kvar_29583079319..3082744 [-], 3426288935817ImcF domain-containing protein  TssM
12Kvar_29593082728..3083867 [-], 1140288935818hypothetical protein 
13Kvar_29603083864..3084121 [-], 258288935819PaaR repeat-containing protein  PAAR
14Kvar_29613084142..3086595 [-], 2454288935820hypothetical protein 
15Kvar_29623086583..3087104 [-], 522288935821lipoprotein 
16Kvar_29633087173..3087703 [-], 531288935822lipoprotein 
17Kvar_29643087771..3088283 [-], 513288935823lipoprotein 
18Kvar_29653088351..3088872 [-], 522288935824lipoprotein 
19Kvar_29663088940..3089467 [-], 528288935825lipoprotein 
20Kvar_29673089531..3090310 [-], 780288935826hypothetical protein 
21Kvar_29683090311..3092689 [-], 2379288935827Rhs element Vgr protein  TssI
22Kvar_29693092682..3095336 [-], 2655288935828type VI secretion ATPase, ClpV1 family  TssH
23Kvar_29703095601..3096092 [-], 492288935829Hcp1 family type VI secretion system effector  TssD
24Kvar_29713096097..3097803 [-], 1707288935830OmpA/MotB domain-containing protein  TagL
25Kvar_29723097800..3098489 [-], 690288935831type IV / VI secretion system protein, DotU family  TssL
26Kvar_29733098486..3099829 [-], 1344288935832type VI secretion protein  TssK
27Kvar_29743099839..3101383 [-], 1545288935833EvpB family type VI secretion protein  TssC
28Kvar_29753101426..3101917 [-], 492288935834type VI secretion protein  TssB
29Kvar_29763102544..3103113 [+], 570288935835intracellular protease PfpI family 
30Kvar_29773103271..3104032 [-], 762288935836short-chain dehydrogenase/reductase SDR 
31Kvar_29783104142..3105056 [+], 915288935837LysR family transcriptional regulator 
32Kvar_29793105359..3105547 [+], 189288935838hypothetical protein 
33Kvar_29803105601..3106071 [-], 471288935839anti-sigma regulatory factor, serine/threonine protein kinase 
34Kvar_29813106064..3106402 [-], 339288935840anti-sigma-factor antagonist 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Kvar_29703095601..3096092 [-], 492288935829Hcp1 family type VI secretion system effector EC042_4529

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Proteins        Genes
(1) Sarris PF et al. (2011). Distribution of the putative type VI secretion system core genes in Klebsiella spp. Infect Genet Evol. 11(1):157-66. [PudMed:20932940] in_silico
in_silico This literature contains bioinformatics investigation