I. Summary

SecReT6 ID	38
Strain	Vibrio vulnificus CMCP6
Replicon	chromosome II [Browse all T6SS(s) in this replicon]
Accession	NC_004460
Location	454915..489055
Comment
Function	N/A
T6SS Type	Type i; subtype i5
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	2	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	VV2_0416	450819..451718 [-], 900	27366854	hypothetical protein
2	VV2_0419	452116..452595 [-], 480	326424230	hypothetical protein
3	VV2_0420	452756..453367 [-], 612	326424231	transposase
4	VV2_0421	453447..453674 [-], 228	27366858	transposase
5	VV2_0422	453809..454318 [-], 510	27366859	hypothetical protein
6	VV2_0423	454315..454470 [-], 156	27366860	hypothetical protein
7	VV2_0424	454476..454859 [-], 384	27366861	helicase subunit of the DNA excision repair complex
8	VV2_0425	454907..459340 [-], 4434	27366862	Rhs family protein
9	VV2_0426	459341..460249 [-], 909	27366863	NAD/NADP transhydrogenase subunit beta
10	VV2_0427	460250..460540 [-], 291	27366864	hypothetical protein	PAAR
11	VV2_0428	460550..462385 [-], 1836	326424232	hypothetical protein	TssI
12	VV2_0429	462440..462919 [-], 480	27366866	hemolysin-coregulated protein	TssD
13	VV2_0430 (clpV)	463135..465699 [-], 2565	27366867	type VI secretion ATPase, ClpV1 family	TssH
14	VV2_0431	465713..466681 [-], 969	27366868	hypothetical protein	TssG
15	VV2_0432	466678..468504 [-], 1827	27366869	protein ImpG/VasA	TssF
16	VV2_0433	468501..468974 [-], 474	27366870	hypothetical protein	TssE
17	VV2_0434	468971..469774 [-], 804	27366871	protein of avirulence locus ImpE	TagJ
18	VV2_0435	469785..471278 [-], 1494	27366872	hypothetical protein	TssC
19	VV2_0436	471323..472816 [-], 1494	27366873	hypothetical protein	TssC
20	VV2_0437	472828..473340 [-], 513	27366874	hypothetical protein	TssB
21	VV2_0438	473357..474490 [-], 1134	27366875	hypothetical protein	TssA
22	VV2_0439	474490..475323 [-], 834	27366876	serine/threonine protein phosphatase
23	VV2_0440	475295..475990 [-], 696	27366877	protein phosphatase ImpM
24	VV2_0441	475972..479496 [-], 3525	326424233	IcmF-like protein	TssM
25	VV2_0442	479474..480802 [-], 1329	27366879	flagellar motor protein	TssL
26	VV2_0443	480811..482133 [-], 1323	326424234	hypothetical protein	TssK
27	VV2_0444	482157..482612 [-], 456	27366881	Type VI secretion lipoprotein/VasD	TssJ
28	VV2_0445	482613..483830 [-], 1218	326424235	hypothetical protein	Fha
29	VV2_0446	484146..486314 [+], 2169	326424236	serine/threonine protein kinase
30	VV2_0447	486378..486995 [-], 618	27366884	glutathione S-transferase
31	VV2_0448	487096..487683 [+], 588	27366885	transcriptional regulator
32	VV2_0449	487680..488078 [+], 399	27366886	DNA-binding protein
33	VV2_0450	488082..488345 [-], 264	27366887	hypothetical protein
34	VV2_0451	488345..488575 [-], 231	27366888	hypothetical protein
35	VV2_0452	488703..489047 [-], 345	27366889	Type III effector HopPmaJ
36	VV2_0453	489309..490907 [+], 1599	326424237	signal transduction protein
37	VV2_0454	491007..491339 [-], 333	27366891	pterin-4-alpha-carbinolamine dehydratase
38	VV2_0455 (phhA)	491332..492123 [-], 792	27366892	phenylalanine 4-monooxygenase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

VPA1027

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	VV2_0429	462440..462919 [-], 480	27366866	hemolysin-coregulated protein	VPA1027

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation