I. Summary

SecReT6 ID	383
Strain	Escherichia coli O55:H7 str. CB9615
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_013941
Location	243492..266945
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	2	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	G2583_0218 (rnhA)	239045..239512 [-], 468	291281031	RNase HI
2	G2583_0219 (dnaQ)	239577..240308 [+], 732	291281032	DNA polymerase III epsilon subunit
3	G2583_0221 (yafT)	240845..241645 [+], 801	291281033	hypothetical protein
4	G2583_0222	241830..242126 [-], 297	291281034	hypothetical protein
5	G2583_0223	242123..242578 [-], 456	291281035	hypothetical protein
6	G2583_0224	242575..243471 [-], 897	291281036	hypothetical protein
7	G2583_0225 (yhhZ)	243492..243971 [-], 480	291281037	hypothetical protein	TssD
8	G2583_0226 (impA)	243937..245436 [-], 1500	291281038	ImpA domain protein	TssA
9	G2583_0227	245357..248821 [-], 3465	291281039	macrophage toxin	TssM
10	G2583_0228 (impA)	248900..250312 [-], 1413	291281040	ImpA domain protein	TssA
11	G2583_0229	250317..251060 [-], 744	291281041	type VI secretion-associated protein, VC_A0118 family
12	G2583_0230 (clpB)	251057..253840 [-], 2784	291281042	type VI secretion ATPase, ClpV1 family	TssH
13	G2583_0231	253849..254610 [-], 762	291281043	hypothetical protein	TssL
14	G2583_0232	254615..255946 [-], 1332	291281044	hypothetical protein	TssK
15	G2583_0233	255949..256473 [-], 525	291281045	type VI secretion lipoprotein, VC_A0113 family	TssJ
16	G2583_0234	256470..257480 [-], 1011	291281046	hypothetical protein	Fha
17	G2583_0235	257774..258856 [-], 1083	291281047	hypothetical protein	TssG
18	G2583_0236	258820..260670 [-], 1851	291281048	hypothetical protein	TssF
19	G2583_0237	260674..261087 [-], 414	291281049	hypothetical protein	TssE
20	G2583_0239	262620..262844 [-], 225	291281050	hypothetical protein	TssC
21	G2583_0240	262879..263379 [-], 501	291281051	hypothetical protein	TssB
22	G2583_0241	263806..263949 [+], 144	291281052	hypothetical protein
23	G2583_0242	264076..264594 [+], 519	291281053	Hcp	TssD
24	G2583_0243	264627..264764 [+], 138	291281054	hypothetical protein
25	G2583_0244 (vgrG)	264804..266945 [+], 2142	291281055	VgrG	TssI

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ECA4275

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	G2583_0242	264076..264594 [+], 519	291281053	Hcp	ECA4275

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Proteins        Genes

N/A

N/A