I. Summary
SecReT6 ID396 insolico
StrainEnterobacter cloacae subsp. cloacae ATCC 13047
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECL_017961814799..1815305 [-], 507296102157thiol peroxidase 
2ECL_017971815413..1816378 [+], 966296102158mandelate racemase/muconate lactonizing protein 
3ECL_017981816369..1817082 [-], 714296102159murein peptide amidase A 
4ECL_017991817265..1818881 [+], 1617296102160putative transport periplasmic protein 
5ECL_018001818962..1819087 [-], 126296102161hypothetical protein 
6ECL_01801 (impB)1819466..1819957 [+], 492296102162type VI secretion system protein ImpB  TssB
7ECL_018021819993..1821540 [+], 1548296102163type VI secretion protein EvpB  TssC
8ECL_018031821558..1822898 [+], 1341296102164hypothetical protein  TssK
9ECL_018041822895..1823587 [+], 693296102165putative OmpA-family membrane protein  TssL
10ECL_018051823680..1825107 [+], 1428296102166OmpA/MotB domain-containing protein  TagL
11ECL_01806 (vasG)1825059..1827341 [+], 2283296102167type VI secretion system protein VasG  TssH
12ECL_018091830562..1832409 [+], 1848296102168hypothetical protein 
13ECL_018101832427..1832921 [+], 495296102169maltose transport system permease 
14ECL_018111833017..1833250 [+], 234296102170hypothetical protein 
15ECL_018121833664..1834872 [+], 1209296102171putative structural protein 
16ECL_01813 (impL)1834869..1838342 [+], 3474296102172type VI secretion system protein ImpL  TssM
17ECL_01814 (vasJ)1838342..1839940 [+], 1599296102173type VI secretion system protein VasJ  TssA
18ECL_018151839974..1840165 [+], 192296102174hypothetical protein  PAAR
19ECL_018161840167..1841135 [+], 969296102175putative IS903 transposase 
20ECL_01817 (impG)1841208..1842659 [+], 1452296102176type VI secretion system protein ImpG  TssF
21ECL_01818 (impH)1842623..1843708 [+], 1086296102177type VI secretion system protein ImpH  TssG
22ECL_01819 (vasD)1843686..1844231 [+], 546296102178type VI secretion system protein VasD  TssJ
23ECL_018201844231..1844686 [+], 456296102179type VI secretion system protein  TssE
24ECL_01821 (vasL)1844710..1846026 [+], 1317296102180type VI secretion system protein VasL  TssA
25ECL_018221846145..1846624 [+], 480296102181hypothetical protein 
26ECL_018231846659..1847222 [-], 564296102182putative intracellular protease/amidase 
27ECL_018241847440..1847580 [-], 141296102183hypothetical protein 
28ECL_018251847655..1848887 [-], 1233296102184PAS/PAC sensor-containing diguanylate cyclase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
EC042_4529 , Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECL_021552199781..2200263 [+], 483296102506Hcp family type VI secretion system effector EC042_4529
2ECL_039844091478..4091966 [-], 489296104321Hcp family type VI secretion system effector Hcp

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Proteins        Genes