I. Summary
SecReT6 ID403 insolico
StrainErwinia billingiae Eb661
Repliconchromosome [Browse all T6SS(s) in this replicon]
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1EbC_392304368780..4369772 [+], 993300718498LacI family transcriptional regulator 
2EbC_392404369923..4370864 [+], 942300718499D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit 
3EbC_392504370951..4372282 [+], 1332300718500major facilitator superfamily protein 
4EbC_392604372900..4374402 [+], 1503300718501OmpA family protein  TagL
5EbC_392704374417..4376015 [+], 1599300718502hypothetical protein 
6EbC_392804376012..4376842 [+], 831300718503hypothetical protein 
7EbC_392904377292..4379364 [+], 2073300718504fusaric acid resistance protein 
8EbC_393004379399..4379686 [-], 288300718505XRE family transcripitonal regulator 
9EbC_39310 (api4)4379689..4380357 [-], 669300718506hypothetical protein 
10EbC_393204380350..4381066 [-], 717300718507phage intergrase 
11EbC_393304382722..4385220 [+], 2499300718508type VI secretion system, Rhs element Vgr protein  TssI
12EbC_393404385237..4386190 [+], 954300718509hypothetical protein 
13EbC_393504386193..4387059 [+], 867300718510hypothetical protein 
14EbC_393604387063..4389099 [+], 2037300718511hypothetical protein 
15EbC_393704389096..4389353 [+], 258300718512hypothetical protein  PAAR
16EbC_393804389353..4390792 [+], 1440300718513hypothetical protein 
17EbC_393904390795..4393893 [+], 3099300718514type VI secretion system, ImcF domain-containing protein  TssM
18EbC_394004393907..4395682 [+], 1776300718515type VI secretion protein, VCA0110 family  TssF
19EbC_394104395682..4396707 [+], 1026300718516hypothetical protein  TssG
20EbC_394204396733..4396867 [+], 135300718517hypothetical protein 
21EbC_394304397024..4397896 [+], 873300718518hypothetical protein 
22EbC_394404398274..4398603 [+], 330300718519hypothetical protein 
23EbC_39450 (hsdR)4398927..4401362 [+], 2436300718520type I restriction enzyme EcoAI R protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SMA2263 , Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1EbC_05850687947..688429 [+], 483300715173hypothetical protein SMA2263
2EbC_157801783364..1783849 [+], 486300716157type VI family secretion system effector, Hcp1, virulence factor for secretion apparatus Hcp

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Proteins        Genes
(1) De Maayer P et al. (2011). Comparative genomics of the Type VI secretion systems of Pantoea and Erwinia species reveals the presence of putative effector islands that may be translocated by the VgrG and Hcp proteins. BMC Genomics. 12:576. [PudMed:22115407] in_silico
in_silico This literature contains bioinformatics investigation