I. Summary
SecReT6 ID409 insolico
StrainDickeya dadantii 3937
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Dda3937_008231569556..1569957 [+], 402307130211hypothetical protein 
2Dda3937_008221570055..1571092 [+], 1038307130212hypothetical protein 
3Dda3937_008211571103..1571450 [+], 348307130213hypothetical protein 
4Dda3937_008201571534..1571716 [-], 183307130214hypothetical protein 
5Dda3937_008191572150..1573313 [+], 1164307130215peptidase M20D, amidohydrolase 
6Dda3937_008181573440..1573739 [-], 300307130216hypothetical protein 
7Dda3937_045111573951..1574208 [-], 258307130217hypothetical protein 
8Dda3937_008171574284..1574787 [+], 504307130218protein ImpB  TssB
9Dda3937_008161574819..1576297 [+], 1479307130219SciI protein  TssC
10Dda3937_008151576304..1576735 [+], 432307130220hypothetical protein  TssE
11Dda3937_008141576738..1578504 [+], 1767307130221hypothetical protein  TssF
12Dda3937_008131578468..1579481 [+], 1014307130222SciB protein  TssG
13Dda3937_008121579418..1580698 [+], 1281307130223hypothetical protein  Fha
14Dda3937_008111580698..1581234 [+], 537307130224lipoprotein  TssJ
15Dda3937_008101581237..1582574 [+], 1338307130225protein ImpJ  TssK
16Dda3937_008091582591..1583367 [+], 777307130226chemotaxis motB protein  TssL
17Dda3937_008081583383..1586001 [+], 2619307130227ClpB protein  TssH
18Dda3937_008071586004..1587542 [+], 1539307130228response regulator of zinc sigma-54-dependent two-component system 
19Dda3937_008061587518..1588105 [+], 588307130229hypothetical protein 
20Dda3937_008051588093..1589556 [+], 1464307130230hypothetical protein  TssA
21Dda3937_008041589582..1593079 [+], 3498307130231IcmF-like protein  TssM
22Dda3937_008031593131..1594564 [+], 1434307130232hypothetical protein  TssA
23Dda3937_008021594634..1596001 [+], 1368307130233hypothetical protein 
24Dda3937_008011595895..1596956 [+], 1062307130234hypothetical protein 
25Dda3937_008001597050..1597910 [-], 861307130235D-alanine aminotransferase 
26Dda3937_007991597910..1598920 [-], 1011307130236mandelate racemase/muconate lactonizing protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
Dda3937_01758 , ECA3427, ECA4275, ECA2866, ECA3427, Dda3937_02773, ECA3427, ECA4275

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Dda3937_01758907392..911696 [-], 4305307129607Rhs-family protein Dda3937_01758
2Dda3937_01760912129..913982 [-], 1854307129609Rhs accessory genetic element ECA3427
3Dda3937_01761(hcpA)914093..914611 [-], 519307129610hypothetical protein ECA4275
4Dda3937_00833(hcpB)1554817..1555335 [+], 519307130200hypothetical protein ECA2866
5Dda3937_008321555504..1557540 [+], 2037307130201VgrG protein ECA3427
6Dda3937_027733131418..3135728 [-], 4311307131672Rhs-family protein Dda3937_02773
7Dda3937_027713136161..3138014 [-], 1854307131674Rhs accessory genetic element ECA3427
8Dda3937_027703138127..3138645 [-], 519307131675hypothetical protein ECA4275

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Proteins        Genes

Homology Immunity protein list
Dda3937_01757, Dda3937_04645

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Dda3937_01757906975..907382 [-], 408307129606hypothetical protein Dda3937_01757
2Dda3937_046453130907..3131407 [-], 501307131671hypothetical protein Dda3937_04645

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Proteins        Genes
(1) Koskiniemi S et al. (2013). Rhs proteins from diverse bacteria mediate intercellular competition. Proc Natl Acad Sci U S A. 110(17):7032-7. [PudMed:23572593] experimental
experimental This literature contains experimental investigation