I. Summary

SecReT6 ID	412
Strain	Achromobacter xylosoxidans A8
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_014640
Location	6106103..6145441
Comment
Function	N/A
T6SS Type	Type i; subtype i4b
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	3	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	AXYL_05683	6101685..6102614 [-], 930	311108844	hypothetical protein
2	AXYL_05684	6102614..6105250 [-], 2637	311108845	hypothetical protein
3	AXYL_05685	6105240..6106085 [-], 846	311108846	hypothetical protein
4	AXYL_05686	6106103..6108805 [-], 2703	311108847	Rhs element Vgr family protein 1	TssI
5	AXYL_05687 (clpB2)	6108820..6111519 [-], 2700	311108848	chaperone protein ClpB	TssH
6	AXYL_05688	6111538..6112620 [-], 1083	311108849	hypothetical protein	TssG
7	AXYL_05689	6112593..6114431 [-], 1839	311108850	hypothetical protein	TssF
8	AXYL_05690	6114486..6114974 [-], 489	311108851	type VI secretion system, lysozyme-related family protein 1	TssE
9	AXYL_05691	6115037..6115540 [-], 504	311108852	type VI secretion system effector, Hcp1 family protein	TssD
10	AXYL_05692	6115581..6117074 [-], 1494	311108853	hypothetical protein	TssC
11	AXYL_05693	6117067..6117591 [-], 525	311108854	hypothetical protein	TssB
12	AXYL_05694	6117636..6118325 [-], 690	311108855	tetratricopeptide repeat family protein 12
13	AXYL_05695	6118626..6119132 [+], 507	311108856	hypothetical protein	TssJ
14	AXYL_05696	6119214..6120560 [+], 1347	311108857	hypothetical protein	TssK
15	AXYL_05697	6120570..6121349 [+], 780	311108858	type IV/VI secretion system protein, DotU family domain-containing protein	TssL
16	AXYL_05698	6121389..6126590 [+], 5202	311108859	Rhs element Vgr family protein 2	TssI
17	AXYL_05699	6126571..6127197 [+], 627	311108860	hypothetical protein
18	AXYL_05700	6127221..6127571 [-], 351	311108861	hypothetical protein
19	AXYL_05701	6127591..6127953 [-], 363	311108862	hypothetical protein
20	AXYL_05702	6127963..6128331 [-], 369	311108863	hypothetical protein
21	AXYL_05703	6128324..6128512 [-], 189	311108864	hypothetical protein
22	AXYL_05704	6128708..6128806 [-], 99	311108865	hypothetical protein
23	AXYL_05705	6128811..6129167 [-], 357	311108866	hypothetical protein
24	AXYL_05706	6129160..6129513 [-], 354	311108867	hypothetical protein
25	AXYL_05707	6129575..6131959 [-], 2385	311108868	phospholipase D
26	AXYL_05708	6131997..6135302 [-], 3306	311108869	Rhs element Vgr family protein 3	TssI
27	AXYL_05709	6135329..6136219 [-], 891	311108870	hypothetical protein
28	AXYL_05710	6136410..6137261 [+], 852	311108871	D-alanyl-D-alanine carboxypeptidase
29	AXYL_05711	6137290..6138678 [+], 1389	311108872	hypothetical protein
30	AXYL_05712	6138702..6142502 [+], 3801	311108873	hypothetical protein	TssM
31	AXYL_05713	6142499..6143482 [+], 984	311108874	hypothetical protein
32	AXYL_05714	6143485..6144279 [+], 795	311108875	OmpA family protein 4	TagL
33	AXYL_05715	6144335..6145441 [-], 1107	311108876	ImpA-related N-terminal domain-containing protein 1	TssA
34	AXYL_05716	6145615..6145866 [+], 252	311108877	hypothetical protein
35	AXYL_05717	6145903..6146172 [+], 270	311108878	PAAR motif family protein 2	PAAR
36	AXYL_05718	6146169..6146612 [-], 444	311108879	hypothetical protein
37	AXYL_05719	6146928..6148199 [+], 1272	311108880	tetratricopeptide repeat family protein 13
38	AXYL_05720	6148265..6148429 [+], 165	311108881	hypothetical protein
39	AXYL_05721 (mtnN)	6148442..6149197 [-], 756	311108882	MTA/SAH nucleosidase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

BCAL0343

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	AXYL_05691	6115037..6115540 [-], 504	311108852	type VI secretion system effector, Hcp1 family protein	BCAL0343

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Proteins        Genes

N/A

N/A