SecReT6
I. Summary
SecReT6 ID443 experimental
StrainMethylomonas methanica MC09
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_015572
Location915765..926524
Comment
Functioneffector translocation
T6SS TypeType i; subtype i3
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number110011111
ComponentTssGTssJTssKTssM
Number1000
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1METME_RS04275911243..912682 [+], 1440503583475F0F1 ATP synthase subunit alpha 
2METME_RS04280912679..913491 [+], 813503583476F0F1 ATP synthase subunit gamma 
3METME_RS04285913546..914016 [-], 471908658285hypothetical protein 
4METME_RS04290914136..914531 [+], 396pseudogenehypothetical protein 
5METME_RS04295914912..915655 [+], 744503583479response regulator 
6METME_RS04300 (tssA)915765..916805 [+], 1041503583480type VI secretion system protein TssA 
7METME_RS04305 (tssB)916832..917368 [+], 537503583481type VI secretion system contractile sheath small subunit 
8METME_RS04310 (tssC)917372..918862 [+], 1491503583482type VI secretion system contractile sheath large subunit 
9METME_RS04315918983..919465 [+], 483503583483type VI secretion system tube protein Hcp 
10METME_RS04320919535..920344 [+], 810503583484virulence protein SciE type 
11METME_RS04325 (tssE)920347..920850 [+], 504503583485type VI secretion system baseplate subunit TssE 
12METME_RS04330 (tssF)920853..922736 [+], 1884503583486type VI secretion system baseplate subunit TssF 
13METME_RS04335 (tssG)922700..923764 [+], 1065503583487type VI secretion system baseplate subunit TssG 
14METME_RS04340 (tssH)923804..926524 [+], 2721503583488type VI secretion system ATPase TssH 
15METME_RS04345926790..927809 [+], 1020503583489hypothetical protein 
16METME_RS04350927880..928224 [+], 345752716621hypothetical protein 
17METME_RS04355928491..929525 [+], 1035503583491hypothetical protein 
18METME_RS04360929576..929917 [+], 342503583492hypothetical protein 
19METME_RS04365930046..930384 [+], 339752717890PQQ-binding-like beta-propeller repeat protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
PA2702

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes

Homology Immunity protein list
Metme_3456 (Tsi2_MM)

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
(1) Silverman JM et al. (2013). Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates. Mol Cell. 51(5):584-93. [PudMed:23954347] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation