I. Summary
SecReT6 ID443 experimental
StrainMethylomonas methanica MC09
Repliconchromosome [Browse all T6SS(s) in this replicon]
Functioneffector translocation
T6SS TypeType i; subtype i3
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Metme_0845911243..912682 [+], 1440333982573ATP synthase subunit alpha 
2Metme_0846912679..913491 [+], 813333982574ATP synthase F1 subunit gamma 
3Metme_0847913546..914097 [-], 552333982575hypothetical protein 
4Metme_0848914136..914303 [+], 168333982576hypothetical protein 
5Metme_0849914912..915655 [+], 744333982577response regulator receiver and Hpt phospho transfer protein 
6Metme_0850915765..916805 [+], 1041333982578type VI secretion-associated protein, ImpA family  TssA
7Metme_0851916832..917368 [+], 537333982579type VI secretion protein  TssB
8Metme_0852917372..918862 [+], 1491333982580type VI secretion protein  TssC
9Metme_0853918983..919465 [+], 483333982581type VI secretion system effector  TssD
10Metme_0854919535..920344 [+], 810333982582virulence protein SciE type  TagJ
11Metme_0855920347..920850 [+], 504333982583type VI secretion system lysozyme-like protein  TssE
12Metme_0856920853..922736 [+], 1884333982584type VI secretion protein  TssF
13Metme_0857922700..923764 [+], 1065333982585type VI secretion protein  TssG
14Metme_0858923804..926524 [+], 2721333982586type VI secretion ATPase, ClpV1 family  TssH
15Metme_0859926790..927809 [+], 1020333982587hypothetical protein 
16Metme_0860927895..928224 [+], 330333982588hypothetical protein 
17Metme_0861928491..929525 [+], 1035333982589hypothetical protein 
18Metme_0862929576..929917 [+], 342333982590hypothetical protein 
19Metme_0863929953..930384 [+], 432333982591hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Metme_34573824035..3824514 [-], 480333985114hypothetical protein PA2702
Data from experimental literature

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Proteins        Genes

Homology Immunity protein list
Metme_3456 (Tsi2_MM)

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
(1) Silverman JM et al. (2013). Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates. Mol Cell. 51(5):584-93. [PudMed:23954347] experimental in_silico
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation