I. Summary

SecReT6 ID	448
Strain	Enterobacter aerogenes KCTC 2190
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_015663
Location	4432502..4450053
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	0	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	0	1	0	0

10

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	EAE_20660	4429458..4430204 [+], 747	336250608	DeoR family transcriptional regulator
2	EAE_20665	4430218..4431300 [+], 1083	336250609	oxidoreductase domain-containing protein
3	EAE_20670	4431504..4431698 [+], 195	336250610	hypothetical protein
4	EAE_20675	4431870..4432436 [+], 567	336250611	Pfpi family intracellular protease
5	EAE_20680	4432502..4433842 [-], 1341	336250612	ImpA domain-containing protein	TssA
6	EAE_20685	4433863..4434306 [-], 444	336250613	hypothetical protein	TssE
7	EAE_20690	4434308..4435072 [-], 765	336250614	hypothetical protein	TssJ
8	EAE_20695	4435073..4435642 [-], 570	336250615	hypothetical protein
9	EAE_20700	4435751..4436623 [-], 873	336250616	hypothetical protein
10	EAE_20715	4438176..4438748 [-], 573	336250617	hypothetical protein
11	EAE_20720	4438868..4441255 [-], 2388	336250618	hypothetical protein
12	EAE_20725	4441228..4441800 [-], 573	336250619	hypothetical protein
13	EAE_20730	4441983..4442168 [-], 186	336250620	hypothetical protein
14	EAE_20735	4442155..4442469 [-], 315	336250621	type VI secretion system protein ImpG	TssF
15	EAE_20740	4442539..4444113 [-], 1575	336250622	hypothetical protein	TssA
16	EAE_20745	4444113..4444448 [-], 336	336250623	ImpA family type VI secretion-associated protein	TssI
17	EAE_20750	4444576..4447206 [-], 2631	336250624	type VI secretion ATPase, ClpV1 family protein	TssH
18	EAE_20755	4447373..4447864 [-], 492	336250625	type VI secretion system effector	TssD
19	EAE_20760	4447984..4449519 [-], 1536	336250626	type VI secretion protein EvpB	TssC
20	EAE_20765	4449562..4450053 [-], 492	336250627	type VI secretion system protein ImpB	TssB
21	EAE_20770	4450454..4451836 [-], 1383	336250628	putative porin
22	EAE_20775	4452420..4453874 [+], 1455	336250629	sugar (glycoside-Pentoside-Hexuronide) transporter

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	EAE_20755	4447373..4447864 [-], 492	336250625	type VI secretion system effector	EC042_4529

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Proteins        Genes

N/A

N/A