SecReT6
I. Summary
SecReT6 ID470 insolico
StrainFrancisella tularensis subsp. holarctica OSU18
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_008369
Location102493..123977
Comment
FunctionN/A
T6SS TypeType ii (Type FPI)
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentPdpAPdpBIglEVgrGIglFIglGIglHDotUIglI
Number111101111
ComponentIglJPdpCPdpEIglDIglCIglBIglAPdpD
Number11111110
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1FTH_009798364..98774 [-], 411115314056hypothetical protein 
2FTH_009898795..99187 [-], 393115314057hypothetical protein 
3FTH_0100 (isftu1)99988..100868 [+], 881115314058ISFtu1 transposase 
4FTH_0103 (iglA2)102493..103083 [+], 591115314059intracellular growth locus A protein  IglA
5FTH_0104 (iglB2)103073..104617 [+], 1545115314060intracellular growth locus B protein  IglB
6FTH_0105 (iglC2)104628..105263 [+], 636115314061intracellular growth locus C protein  IglC
7FTH_0106 (iglD2)105284..106480 [+], 1197115314062intracellular growth locus D protein  IglD
8FTH_0107106487..107062 [-], 576115314063hypothetical protein  PdpE
9FTH_0108 (pdpC2)107080..111066 [-], 3987115314064protein PdpC  PdpC
10FTH_0109111106..111879 [-], 774115314065hypothetical protein  IglJ
11FTH_0110111845..112996 [-], 1152115314066hypothetical protein  IglI
12FTH_0111113018..113641 [-], 624115314067hypothetical protein  DotU
13FTH_0112113654..115084 [-], 1431115314068hypothetical protein  IglH
14FTH_0113115097..115618 [-], 522115314069hypothetical protein  IglG
15FTH_0115117355..117849 [-], 495115314070hypothetical protein  VgrG
16FTH_0116117862..118239 [-], 378115314071hypothetical protein  IglE
17FTH_0117 (pdpB2)118229..121510 [-], 3282115314072protein PdpB  PdpB
18FTH_0118 (pdpA2)121515..123977 [-], 2463115314073protein PdpA  PdpA
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
FTL_0118 , FTT_1347

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1FTH_0110111845..112996 [-], 1152115314066hypothetical protein FTL_0118
2FTH_0115117355..117849 [-], 495115314070hypothetical protein FTT_1347

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Proteins        Genes
N/A
N/A