• T6SS
• Effector
• Immunity
• Reference

I. Summary

SecReT6 ID	471
Strain	Francisella tularensis subsp. holarctica OSU18
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_008369
Location	1101418..1122902
Comment
Function	N/A
T6SS Type	Type ii (Type FPI)
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	PdpA	PdpB	IglE	VgrG	IglF	IglG	IglH	DotU	IglI
Number	1	1	1	1	1	1	1	1	1
Component	IglJ	PdpC	PdpE	IglD	IglC	IglB	IglA	PdpD
Number	1	1	1	1	1	1	1	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	FTH_1129 (iglA1)	1101418..1102008 [+], 591	115314909	intracellular growth locus A protein	IglA
2	FTH_1130 (iglB1)	1101998..1103542 [+], 1545	115314910	intracellular growth locus B protein	IglB
3	FTH_1131 (iglC1)	1103559..1104188 [+], 630	115314911	intracellular growth locus C protein	IglC
4	FTH_1132 (iglD1)	1104200..1105405 [+], 1206	115314912	intracellular growth locus D protein	IglD
5	FTH_1133	1105412..1105987 [-], 576	115314913	hypothetical protein	PdpE
6	FTH_1134 (pdpC1)	1106005..1109991 [-], 3987	115314914	protein PdpC	PdpC
7	FTH_1135	1110031..1110804 [-], 774	115314915	hypothetical protein	IglJ
8	FTH_1136	1110770..1111921 [-], 1152	115314916	hypothetical protein	IglI
9	FTH_1137	1111943..1112566 [-], 624	115314917	hypothetical protein	DotU
10	FTH_1138	1112579..1114009 [-], 1431	115314918	hypothetical protein	IglH
11	FTH_1139	1114022..1114543 [-], 522	115314919	hypothetical protein	IglG
12	FTH_1140	1114611..1116275 [-], 1665	115314920	hypothetical protein	IglF
13	FTH_1141	1116280..1116774 [-], 495	115314921	hypothetical protein	VgrG
14	FTH_1142	1116787..1117164 [-], 378	115314922	hypothetical protein	IglE
15	FTH_1143 (pdpB1)	1117154..1120435 [-], 3282	115314923	hypothetical protein	PdpB
16	FTH_1144 (pdpA1)	1120440..1122902 [-], 2463	115314924	hypothetical protein	PdpA

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

FTL_0118 , FTT_1347

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	FTH_1136	1110770..1111921 [-], 1152	115314916	hypothetical protein	FTL_0118
2	FTH_1141	1116280..1116774 [-], 495	115314921	hypothetical protein	FTT_1347

Download FASTA format files

Proteins        Genes

N/A

N/A

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