I. Summary

SecReT6 ID	473
Strain	Francisella tularensis subsp. tularensis WY96-3418
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_009257
Location	520088..545203
Comment
Function	N/A
T6SS Type	Type ii (Type FPI)
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	PdpA	PdpB	IglE	VgrG	IglF	IglG	IglH	DotU	IglI
Number	1	1	1	1	1	1	1	1	1
Component	IglJ	PdpC	PdpE	IglD	IglC	IglB	IglA	PdpD
Number	1	1	1	1	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	FTW_0530	516949..517829 [+], 881	134301594	transposase ISFtu1
2	FTW_0533 (anmK)	518843..519856 [+], 1014	134301595	anhydro-N-acetylmuramic acid kinase
3	FTW_0534 (pdpD2)	520088..523675 [+], 3588	134301596	pathogenicity determinant protein D, pdpD	PdpD
4	FTW_0535 (iglA2)	523756..524310 [+], 555	134301597	intracellular growth locus, iglA	IglA
5	FTW_0536 (iglB2)	524324..525844 [+], 1521	134301598	intracellular growth locus iglB	IglB
6	FTW_0537 (iglC2)	525855..526490 [+], 636	134301599	intracellular growth locus iglC	IglC
7	FTW_0538 (iglD2)	526511..527707 [+], 1197	134301600	intracellular growth locus iglD	IglD
8	FTW_0539	527714..528289 [-], 576	134301601	hypothetical protein	PdpE
9	FTW_0540 (pdpC2)	528307..532293 [-], 3987	134301602	pathogenicity determinant protein pdpC2	PdpC
10	FTW_0541	532333..533049 [-], 717	134301603	hypothetical protein	IglJ
11	FTW_0542	533072..534223 [-], 1152	134301604	hypothetical protein	IglI
12	FTW_0543	534245..534868 [-], 624	134301605	hypothetical protein	DotU
13	FTW_0544	534881..536311 [-], 1431	134301606	hypothetical protein	IglH
14	FTW_0545	536324..536845 [-], 522	134301607	hypothetical protein	IglG
15	FTW_0546	536846..538576 [-], 1731	134301608	hypothetical protein	IglF
16	FTW_0547	538581..539075 [-], 495	134301609	hypothetical protein	VgrG
17	FTW_0548	539088..539465 [-], 378	134301610	putative lipoprotein	IglE
18	FTW_0549 (pdpB2)	539455..542736 [-], 3282	134301611	pathogenicity determinant protein pdpB2	PdpB
19	FTW_0550 (pdpA2)	542741..545203 [-], 2463	134301612	pathogenicity determinant protein, pdpA	PdpA

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

FTL_0118 , FTT_1347

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	FTW_0542	533072..534223 [-], 1152	134301604	hypothetical protein	FTL_0118
2	FTW_0547	538581..539075 [-], 495	134301609	hypothetical protein	FTT_1347

Download FASTA format files

Proteins        Genes

N/A

N/A