I. Summary
SecReT6 ID473 insolico
StrainFrancisella tularensis subsp. tularensis WY96-3418
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType ii (Type FPI)
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1FTW_0530516949..517829 [+], 881134301594transposase ISFtu1 
2FTW_0533 (anmK)518843..519856 [+], 1014134301595anhydro-N-acetylmuramic acid kinase 
3FTW_0534 (pdpD2)520088..523675 [+], 3588134301596pathogenicity determinant protein D, pdpD  PdpD
4FTW_0535 (iglA2)523756..524310 [+], 555134301597intracellular growth locus, iglA  IglA
5FTW_0536 (iglB2)524324..525844 [+], 1521134301598intracellular growth locus iglB  IglB
6FTW_0537 (iglC2)525855..526490 [+], 636134301599intracellular growth locus iglC  IglC
7FTW_0538 (iglD2)526511..527707 [+], 1197134301600intracellular growth locus iglD  IglD
8FTW_0539527714..528289 [-], 576134301601hypothetical protein  PdpE
9FTW_0540 (pdpC2)528307..532293 [-], 3987134301602pathogenicity determinant protein pdpC2  PdpC
10FTW_0541532333..533049 [-], 717134301603hypothetical protein  IglJ
11FTW_0542533072..534223 [-], 1152134301604hypothetical protein  IglI
12FTW_0543534245..534868 [-], 624134301605hypothetical protein  DotU
13FTW_0544534881..536311 [-], 1431134301606hypothetical protein  IglH
14FTW_0545536324..536845 [-], 522134301607hypothetical protein  IglG
15FTW_0546536846..538576 [-], 1731134301608hypothetical protein  IglF
16FTW_0547538581..539075 [-], 495134301609hypothetical protein  VgrG
17FTW_0548539088..539465 [-], 378134301610putative lipoprotein  IglE
18FTW_0549 (pdpB2)539455..542736 [-], 3282134301611pathogenicity determinant protein pdpB2  PdpB
19FTW_0550 (pdpA2)542741..545203 [-], 2463134301612pathogenicity determinant protein, pdpA  PdpA
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
FTL_0118 , FTT_1347

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1FTW_0542533072..534223 [-], 1152134301604hypothetical protein FTL_0118
2FTW_0547538581..539075 [-], 495134301609hypothetical protein FTT_1347

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Proteins        Genes