SecReT6
I. Summary
SecReT6 ID474 insolico
StrainFrancisella tularensis subsp. holarctica FTNF002-00
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_009749
Location102588..124036
Comment
FunctionN/A
T6SS TypeType ii (Type FPI)
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentPdpAPdpBIglEVgrGIglFIglGIglHDotUIglI
Number111101111
ComponentIglJPdpCPdpEIglDIglCIglBIglAPdpD
Number11111110
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1FTA_011198422..98832 [-], 411156501480hypothetical protein 
2FTA_011298853..99245 [-], 393156501481lipoprotein 
3FTA_0114100047..100927 [+], 881169656484transposase ISFTu1 
4FTA_0116100928..101800 [-], 873156501485major facilitator transporter 
5FTA_0119 (iglA1)102588..103142 [+], 555156501488intracellular growth locus subunit A  IglA
6FTA_0120 (iglB1)103156..104676 [+], 1521156501489intracellular growth locus subunit B  IglB
7FTA_0121 (iglC1)104687..105322 [+], 636156501490intracellular growth locus subunit C  IglC
8FTA_0122 (iglD1)105343..106539 [+], 1197156501491intracellular growth locus subunit D  IglD
9FTA_0123106546..107121 [-], 576156501492hypothetical protein  PdpE
10FTA_0124 (pdpC1)107139..111125 [-], 3987156501493pathogenicity determinant protein PdpC  PdpC
11FTA_0125111165..111938 [-], 774156501494hypothetical protein  IglJ
12FTA_0126111904..113055 [-], 1152156501495hypothetical protein  IglI
13FTA_0127113077..113700 [-], 624156501496hypothetical protein  DotU
14FTA_0128113713..115143 [-], 1431156501497hypothetical protein  IglH
15FTA_0129115156..115677 [-], 522169656485hypothetical protein  IglG
16FTA_0131117414..117908 [-], 495156501500hypothetical protein  VgrG
17FTA_0132117921..118298 [-], 378156501501lipoprotein  IglE
18FTA_0133 (pdpB1)118288..121569 [-], 3282156501502pathogenicity deteminant protein PdpB  PdpB
19FTA_0134 (pdpA1)121574..124036 [-], 2463156501503pathogenicity deteminant protein PdpA  PdpA
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
FTL_0118 , FTT_1347

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1FTA_0126111904..113055 [-], 1152156501495hypothetical protein FTL_0118
2FTA_0131117414..117908 [-], 495156501500hypothetical protein FTT_1347

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Proteins        Genes
N/A
N/A