I. Summary

SecReT6 ID	476
Strain	Francisella philomiragia subsp. philomiragia ATCC 25017
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_010336
Location	1486538..1507202
Comment
Function	N/A
T6SS Type	Type ii (Type FPI)
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	PdpA	PdpB	IglE	VgrG	IglF	IglG	IglH	DotU	IglI
Number	1	1	1	1	1	1	1	1	1
Component	IglJ	PdpC	PdpE	IglD	IglC	IglB	IglA	PdpD
Number	1	0	0	1	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	Fphi_1360	1482468..1483925 [-], 1458	167627586	alpha,alpha-trehalase
2	Fphi_1361	1483928..1485136 [-], 1209	167627587	fucose permease-like protein
3	Fphi_1362 (anmK)	1485309..1486457 [+], 1149	167627588	anhydro-N-acetylmuramic acid kinase
4	Fphi_1363	1486538..1490272 [+], 3735	167627589	hypothetical protein	PdpD
5	Fphi_1364	1490356..1490919 [+], 564	167627590	intracellular growth locus protein A	IglA
6	Fphi_1365	1490932..1492452 [+], 1521	167627591	intracellular growth locus subunit B	IglB
7	Fphi_1366	1492470..1493099 [+], 630	167627592	intracellular growth locus subunit C	IglC
8	Fphi_1367	1493123..1494319 [+], 1197	167627593	intracellular growth locus protein D	IglD
9	Fphi_1368	1494332..1495051 [-], 720	167627594	hypothetical protein	IglJ
10	Fphi_1369	1495069..1496262 [-], 1194	167627595	hypothetical protein	IglI
11	Fphi_1370	1496277..1496897 [-], 621	167627596	hypothetical protein	DotU
12	Fphi_1371	1496912..1498339 [-], 1428	167627597	hypothetical protein	IglH
13	Fphi_1372	1498351..1498872 [-], 522	167627598	hypothetical protein	IglG
14	Fphi_1373	1498872..1500587 [-], 1716	167627599	hypothetical protein	IglF
15	Fphi_1374	1500593..1501087 [-], 495	167627600	hypothetical protein	VgrG
16	Fphi_1375	1501100..1501477 [-], 378	167627601	hypothetical protein	IglE
17	Fphi_1376	1501467..1504736 [-], 3270	167627602	hypothetical protein	PdpB
18	Fphi_1377	1504740..1507202 [-], 2463	167627603	hypothetical protein	PdpA

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

FTN_1312

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	Fphi_1374	1500593..1501087 [-], 495	167627600	hypothetical protein	FTN_1312

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Proteins        Genes

N/A

N/A