SecReT6
I. Summary
SecReT6 ID485 insolico
StrainEscherichia coli 042
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_017626
Location243529..266516
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121111
ComponentTssGTssJTssKTssM
Number1111
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1EC042_RS01110 (gloB)239097..239852 [-], 756446975480hydroxyacylglutathione hydrolase 
2EC042_RS01115239886..240608 [+], 723481023496class I SAM-dependent methyltransferase 
3EC042_RS01120 (rnhA)240605..241072 [-], 468446840627ribonuclease HI 
4EC042_RS01125 (dnaQ)241137..241868 [+], 732585203913DNA polymerase III subunit epsilon 
5EC042_RS01135242404..243189 [+], 786447008904hypothetical protein 
6EC042_RS01140243529..244008 [-], 480445935324Hcp family type VI secretion system effector  TssD
7EC042_RS01145244026..245384 [-], 1359445995948type VI secretion system ImpA family N-terminal domain-containing protein  TssA
8EC042_RS01150 (tssM)245395..248832 [-], 34381511003915type VI secretion system membrane subunit TssM 
9EC042_RS01155 (tssA)248942..250384 [-], 1443485665474type VI secretion system protein TssA  TssA
10EC042_RS01160 (tagO)250389..251132 [-], 744446010989type VI secretion system-associated protein TagO 
11EC042_RS01165 (tssH)251129..253861 [-], 2733446536956type VI secretion system ATPase TssH  TssH
12EC042_RS01170 (icmH)253871..254644 [-], 774447203013type IVB secretion system protein IcmH/DotU  TssL
13EC042_RS01175 (tssK)254649..255995 [-], 1347446146658type VI secretion system baseplate subunit TssK  TssK
14EC042_RS01180 (tssJ)255998..256522 [-], 525446936168type VI secretion system lipoprotein TssJ  TssJ
15EC042_RS01185 (tagH)256519..257811 [-], 1293446355716type VI secretion system-associated FHA domain protein TagH  Fha
16EC042_RS01190 (tssG)257816..258865 [-], 1050446819463type VI secretion system baseplate subunit TssG  TssG
17EC042_RS01195 (tssF)258829..260670 [-], 1842446786139type VI secretion system baseplate subunit TssF  TssF
18EC042_RS01200 (tssE)260676..261101 [-], 426447112413type VI secretion system baseplate subunit TssE  TssE
19EC042_RS01205 (tssC)261106..262590 [-], 1485446033725type VI secretion system contractile sheath large subunit  TssC
20EC042_RS01210 (tssB)262613..263116 [-], 504445963623type VI secretion system contractile sheath small subunit  TssB
21EC042_RS01215263819..264337 [+], 519447065707Hcp family type VI secretion system effector  TssD
22EC042_RS01225 (tssI)264558..266516 [+], 1959485665466type VI secretion system tip protein VgrG  TssI
23EC042_RS01230266516..267355 [+], 840446369142DUF4123 domain-containing protein 
24EC042_RS01235267377..268948 [+], 1572485665464hypothetical protein 
25EC042_RS01240269063..270025 [+], 963446458613hypothetical protein 
26EC042_RS01245270338..271261 [+], 924pseudogeneISAs1 family transposase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog

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Proteins        Genes
N/A
(1) Chaudhuri RR et al. (2010). Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One. 5(1):e8801. [PudMed:20098708] in_silico
 
in_silico This literature contains bioinformatics investigation