I. Summary

SecReT6 ID	485
Strain	Escherichia coli 042
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_017626
Location	243529..266516
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	2	1	1	2	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	EC042_0205 (gloB)	239097..239852 [-], 756	387605682	hydroxyacylglutathione hydrolase
2	EC042_0206	239883..240608 [+], 726	387605683	hypothetical protein
3	EC042_0207 (rnhA)	240605..241072 [-], 468	387605684	ribonuclease HI
4	EC042_0208 (dnaQ)	241128..241868 [+], 741	387605685	DNA polymerase III subunit epsilon
5	EC042_0209	242404..243189 [+], 786	387605686	putative lipoprotein
6	EC042_0210	243529..244008 [-], 480	387605687	putative type VI secretion system protein	TssD
7	EC042_0211	244026..245384 [-], 1359	387605688	putative type VI secretion system protein	TssA
8	EC042_0212	245395..248922 [-], 3528	387605689	putative type VI secretion system protein	TssM
9	EC042_0213	248942..250384 [-], 1443	387605690	putative type VI secretion system protein	TssA
10	EC042_0214	250389..251132 [-], 744	387605691	putative type VI secretion system protein
11	EC042_0215	251129..253861 [-], 2733	387605692	putative type VI secretion system protein	TssH
12	EC042_0216	253871..254644 [-], 774	387605693	putative type VI secretion system protein	TssL
13	EC042_0217	254649..255995 [-], 1347	387605694	putative type VI secretion system protein	TssK
14	EC042_0218	255998..256522 [-], 525	387605695	putative type VI secretion system protein	TssJ
15	EC042_0219	256519..257811 [-], 1293	387605696	putative type VI secretion system protein	Fha
16	EC042_0220	257816..258865 [-], 1050	387605697	putative type VI secretion system protein	TssG
17	EC042_0221	258829..260670 [-], 1842	387605698	putative type VI secretion system protein	TssF
18	EC042_0222	260676..261101 [-], 426	387605699	putative type VI secretion system protein	TssE
19	EC042_0223	261106..262590 [-], 1485	387605700	putative type VI secretion system protein	TssC
20	EC042_0224	262613..263116 [-], 504	387605701	putative type VI secretion system protein	TssB
21	EC042_0225	263819..264337 [+], 519	387605702	putative type VI secretion system protein	TssD
22	EC042_0226	264423..264542 [+], 120	387605703	hypothetical protein
23	EC042_0227	264558..266516 [+], 1959	387605704	Type VI secretion system Rhs/Vgr-family protein	TssI
24	EC042_0228	266516..267355 [+], 840	387605705	putative type VI secretion system protein
25	EC042_0229	267377..268948 [+], 1572	387605706	putative type VI secretion system protein
26	EC042_0230	269063..270025 [+], 963	387605707	putative type VI secretion system protein
27	EC042_0231	270335..271294 [+], 960	387605708	H repeat-associated protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ABG57132

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	EC042_0225	263819..264337 [+], 519	387605702	putative type VI secretion system protein	ABG57132

Download FASTA format files

Proteins        Genes

N/A

(1) Chaudhuri RR et al. (2010). Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One. 5(1):e8801. [PudMed:20098708]

This literature contains bioinformatics investigation