I. Summary
SecReT6 ID486 insolico
StrainEscherichia coli 55989
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1EC55989_33163398367..3400154 [-], 1788218696616UvrD/REP helicase 
2EC55989_33173400348..3401514 [-], 1167218696617hypothetical protein 
3EC55989_33183401747..3402160 [-], 414218696618hypothetical protein 
4EC55989_33193402305..3402739 [-], 435218696619hypothetical protein  TssE
5EC55989_33203402739..3403275 [-], 537218696620hypothetical protein  TssJ
6EC55989_33213403256..3404356 [-], 1101218696621hypothetical protein  TssG
7EC55989_33223404311..3406074 [-], 1764218696622hypothetical protein  TssF
8EC55989_33233406082..3406879 [-], 798218696623hypothetical protein 
9EC55989_33243406776..3408374 [-], 1599218696624hypothetical protein  TssA
10EC55989_33253408374..3411763 [-], 3390218696625hypothetical protein  TssM
11EC55989_33263411756..3412904 [-], 1149218696626hypothetical protein 
12EC55989_33273412908..3413174 [-], 267218696627hypothetical protein  PAAR
13EC55989_33283413206..3413883 [-], 678218696628hypothetical protein 
14EC55989_33293414027..3414704 [-], 678218696629hypothetical protein 
15EC55989_33303414724..3416406 [-], 1683218696630hypothetical protein 
16EC55989_33313416403..3418928 [-], 2526218696631hypothetical protein  TssI
17EC55989_33333419451..3420026 [-], 576218696632hypothetical protein 
18EC55989_33343420014..3422680 [-], 2667218696633chaperone clpB  TssH
19EC55989_33353422840..3423331 [-], 492218696634hypothetical protein  TssD
20EC55989_33363423337..3425163 [-], 1827218696635hypothetical protein  TagL
21EC55989_33373425070..3425789 [-], 720218696636hypothetical protein  TssL
22EC55989_33383425720..3427057 [-], 1338218696637hypothetical protein  TssK
23EC55989_33393427073..3428617 [-], 1545218696638hypothetical protein  TssC
24EC55989_33403428639..3429160 [-], 522218696639hypothetical protein  TssB
25EC55989_33423429643..3429834 [+], 192218696640hypothetical protein 
26EC55989_33433429887..3430195 [-], 309218696641hypothetical protein 
27EC55989_33443430216..3430875 [-], 660218696642hypothetical protein 
28EC55989_33453431148..3431621 [-], 474218696643hypothetical protein 
29EC55989_33463431557..3431946 [-], 390218696644hypothetical protein 
30EC55989_33483432108..3432677 [-], 570218696645hypothetical protein 
31EC55989_33493432881..3433054 [+], 174218696646hypothetical protein 
32EC55989_33503432924..3433127 [-], 204218696647hypothetical protein 
33EC55989_33513433294..3433506 [-], 213218696648hemolysin expression-modulating protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1EC55989_33353422840..3423331 [-], 492218696634hypothetical protein EC042_4529

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Proteins        Genes
(1) Felisberto-Rodrigues C et al. (2011). Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar. PLoS Pathog. 7(11):e1002386. [PudMed:22102820]