I. Summary
SecReT6 ID512 insolico
StrainMethylomicrobium alcaliphilum 20Z
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1MEALZ_19132198835..2200223 [+], 1389357405269Permease of the major facilitator superfamily 
2MEALZ_1914 (ssb)2200478..2200960 [+], 483357405270ssDNA-binding protein 
3MEALZ_1915 (pomA)2201111..2201869 [+], 759357405271chemotaxis protein PomA 
4MEALZ_19162201877..2202707 [+], 831357405272OmpA family protein  TagL
5MEALZ_19172202767..2203348 [+], 582357405273type IV pilus assembly PilZ 
6MEALZ_1918 (birA)2203424..2204413 [+], 990357405274bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase 
7MEALZ_19192204418..2205329 [+], 912357405275transcriptional activator, Baf family (modular protein) 
8MEALZ_19202205333..2206355 [+], 1023357405276hypothetical protein  SPOR
9MEALZ_19212206639..2207487 [+], 849357405277D-alanyl-D-alanine endopeptidase (fragment) 
10MEALZ_19222208230..2209546 [+], 1317357405278ErfK/YbiS/YcfS/YnhG family protein  SPOR
11MEALZ_19232209818..2210531 [-], 714357405279hypothetical protein 
12MEALZ_19242210993..2211712 [-], 720357405280hypothetical protein 
13MEALZ_19252212255..2213724 [+], 1470357405281FHA domain-containing protein  Fha
14MEALZ_19262214107..2215444 [+], 1338357405282type VI secretion protein  TssK
15MEALZ_1927 (ompA)2215450..2216811 [+], 1362357405283hypothetical protein  TssL
16MEALZ_19282216808..2220371 [+], 3564357405284hypothetical protein  TssM
17MEALZ_19292220371..2221969 [+], 1599357405285phosphoprotein phosphatase 
18MEALZ_19302221997..2223049 [+], 1053357405286type VI secretion-associated protein, ImpA family  TssA
19MEALZ_1931 (sciH)2223097..2223627 [+], 531357405287cytoplasmic protein,SciH  TssB
20MEALZ_19322223631..2225130 [+], 1500357405288type VI secretion protein EvpB  TssC
21MEALZ_19332225251..2225742 [+], 492357405289hypothetical protein 
22MEALZ_1934 (sciE)2226088..2226915 [+], 828357405290cytoplasmic protein,sciE  TagJ
23MEALZ_19352226919..2227419 [+], 501357405291hypothetical protein  TssE
24MEALZ_19362227423..2229303 [+], 1881357405292type VI secretion protein  TssF
25MEALZ_19372229357..2230283 [+], 927357405293hypothetical protein  TssG
26MEALZ_1938 (clpV)2230618..2233335 [+], 2718357405294protein ClpV1  TssH
27MEALZ_19392233405..2233935 [+], 531357405295hypothetical protein 
28MEALZ_19402234049..2234663 [+], 615357405296hypothetical protein 
29MEALZ_19412234948..2236891 [+], 1944357405297ImpA family type VI secretion-associated protein  TssI
30MEALZ_19422236902..2237489 [+], 588357405298hypothetical protein 
31MEALZ_19432237822..2238115 [+], 294357405299hypothetical protein  PAAR
32MEALZ_19442238898..2241030 [+], 2133357405300Rhs-family protein  TssI
33MEALZ_19452241263..2241748 [+], 486357405301hypothetical protein 
34MEALZ_19462241750..2242865 [+], 1116357405302hypothetical protein 
35MEALZ_19472242905..2243117 [+], 213357405303hypothetical protein 
36MEALZ_19482243159..2244196 [+], 1038357405304hypothetical protein 
37MEALZ_19492244196..2245326 [+], 1131357405305hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.