SecReT6
I. Summary
SecReT6 ID543 insolico
StrainSalmonella enterica subsp. enterica serovar Typhi str. P-stx-12
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_016832
Location2647188..2693724
Comment
FunctionN/A
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number211121011
ComponentTssGTssJTssKTssM
Number1110
13
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1STBHUCCB_272202642635..2646699 [-], 4065378960750Rhs-family protein  PAAR
2STBHUCCB_272302646718..2647164 [-], 447378960751hypothetical protein 
3STBHUCCB_272402647188..2649377 [-], 2190378960752Rhs-family protein  TssI
4STBHUCCB_272502649855..2650292 [-], 438378960753pathogenicity island protein 
5STBHUCCB_272602650319..2650705 [-], 387378960754hypothetical protein 
6STBHUCCB_272702650732..2650854 [-], 123378960755hypothetical protein 
7STBHUCCB_272802650863..2651324 [-], 462378960756hypothetical protein 
8STBHUCCB_272902651883..2652356 [-], 474378960757hypothetical protein 
9STBHUCCB_273002652341..2652811 [-], 471378960758hypothetical protein 
10STBHUCCB_273102652854..2653621 [-], 768378960759hypothetical protein 
11STBHUCCB_273402657719..2658213 [-], 495378960760hypothetical protein 
12STBHUCCB_273502658245..2658994 [-], 750378960761hypothetical protein 
13STBHUCCB_273602658999..2660300 [-], 1302378960762hypothetical protein  TssL
14STBHUCCB_273702660297..2661640 [-], 1344378960763Type VI secretion protein  TssK
15STBHUCCB_273802661644..2662135 [-], 492378960764Type VI secretion lipoprotein  TssJ
16STBHUCCB_273902662247..2662732 [-], 486378960765hypothetical protein  TssD
17STBHUCCB_274002662969..2663394 [-], 426378960766hypothetical protein  STY0301 (i)
18STBHUCCB_274302665352..2665894 [-], 543378960767Type VI secretion protein  TssB
19STBHUCCB_274402665958..2666248 [-], 291378960768hypothetical protein 
20STBHUCCB_274502666334..2668997 [-], 2664378960769hypothetical protein  TssH
21STBHUCCB_274602669377..2670267 [+], 891378960770hypothetical protein 
22STBHUCCB_274702670254..2671078 [+], 825378960771hypothetical protein  TagJ
23STBHUCCB_274802671075..2671569 [+], 495378960772Type VI secretion system lysozyme-related protein  TssE
24STBHUCCB_274902671585..2673468 [+], 1884378960773Type VI secretion protein  TssF
25STBHUCCB_275002673465..2674460 [+], 996378960774hypothetical protein  TssG
26STBHUCCB_275102674477..2674893 [+], 417378960775ImpA-related N-family protein  TssA
27STBHUCCB_275202674893..2675525 [+], 633378960776ImpA-related N-family protein  TssA
28STBHUCCB_275302676055..2676795 [-], 741378960777DNA polymerase III subunit epsilon 
29STBHUCCB_275402676850..2677317 [+], 468378960778ribonuclease H 
30STBHUCCB_275502677314..2678036 [-], 723378960779hypothetical protein 
31STBHUCCB_275602678071..2678826 [+], 756378960780hydroxyacylglutathione hydrolase 
32STBHUCCB_275702679045..2680265 [+], 1221378960781membrane-bound lytic murein transglycosylase D 
33STBHUCCB_275802680321..2681091 [-], 771378960782S-adenosyl-L-methionine-dependent methyltransferase 
34STBHUCCB_275902681169..2681969 [-], 801378960783hypothetical protein 
35STBHUCCB_276002682101..2683276 [-], 1176378960784major facilitator family transporter 
36STBHUCCB_276102683381..2684295 [+], 915378960785LysR family transcriptional regulator 
37STBHUCCB_276202684316..2685119 [-], 8043789607862,5-diketo-D-gluconic acid reductase B 
38STBHUCCB_276302691151..2693724 [-], 2574378960787hypothetical protein  TssH
39STBHUCCB_276402693854..2694585 [-], 732378960788hypothetical protein 
40STBHUCCB_276502694582..2695562 [-], 981378960789ribosomal large subunit pseudouridine synthase D 
41STBHUCCB_276602695694..2696431 [+], 738378960790hypothetical protein 
42STBHUCCB_276702696703..2697041 [+], 339378960791ribosome-associated inhibitor A 
43STBHUCCB_276802697292..2698452 [+], 1161378960792prephenate dehydratase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
STY2606 , SciK, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STBHUCCB_5270562364..562732 [-], 369378958634hypothetical protein STY2606
2STBHUCCB_273902662247..2662732 [-], 486378960765hypothetical protein SciK
3STBHUCCB_321803120957..3121442 [-], 486378961225hypothetical protein Hcp

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Proteins        Genes

Homology Immunity protein list
STY2607, STY0301

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STBHUCCB_5260561846..562364 [-], 519378958633hypothetical protein STY2607
2STBHUCCB_274002662969..2663394 [-], 426378960766hypothetical protein STY0301

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Proteins        Genes
N/A