I. Summary
SecReT6 ID550 insolico
StrainSalmonella enterica subsp. enterica serovar Typhimurium str. D23580
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1STMMW_02591299910..301277 [-], 1368378443706membrane-bound lytic murein transglycosylase D 
2STMMW_02601301349..302104 [-], 756378443707hydroxyacylglutathione hydrolase 
3STMMW_02611302139..302861 [+], 723378443708hypothetical protein 
4STMMW_02621302858..303325 [-], 468378443709RNase H 
5STMMW_02631303389..304120 [+], 732378443710DNA polymerase III epsilon subunit 
6STMMW_02641304651..305706 [-], 1056378443711pathogenicity island protein  TssA
7STMMW_02651305717..306712 [-], 996378443712type VI secretion protein  TssG
8STMMW_02661306709..308592 [-], 1884378443713type VI system protein  TssF
9STMMW_02671308608..309102 [-], 495378443714putative type VI system cytoplasmic protein  TssE
10STMMW_02691309099..309923 [-], 825378443715putative type VI secretion system protein  TagJ
11STMMW_02701309910..310812 [-], 903378443716hypothetical protein 
12STMMW_02711311180..313819 [+], 2640378443717type VI system ATPase  TssH
13STMMW_02731313919..314461 [+], 543378443718putative type VI secretion system protein  TssB
14STMMW_02741314485..315978 [+], 1494378443719type VI system secreted protein  TssC
15STMMW_02751316041..316151 [+], 111378443720invasol 
16STMMW_02771316164..316610 [+], 447378443721hypothetical protein 
17STMMW_02791316864..317349 [+], 486378443722putative hemolysin-coregulated protein  TssD
18STMMW_02811317654..318139 [+], 486378443723hypothetical protein  STM0277 (e)
19STMMW_02831318124..318507 [+], 384378443724hypothetical protein  STM0278 (i)
20STMMW_02841318650..319135 [+], 486378443725putative hemolysin-coregulated protein  TssD
21STMMW_02851319202..319738 [+], 537378443726putative lipoprotein  TssJ
22STMMW_02861319742..321085 [+], 1344378443727putative type VI secretion protein  TssK
23STMMW_02871321082..322386 [+], 1305378443728putative type VI system protein  TssL
24STMMW_02881322391..323164 [+], 774378443729putative inner membrane protein 
25STMMW_02891323355..323798 [+], 444378443730putative shiga-like toxin A subunit 
26STMMW_02901323832..327701 [+], 3870378443731type VI system protein  TssM
27STMMW_02911327701..328489 [+], 789378443732hypothetical protein 
28STMMW_02921328486..328902 [+], 417378443733hypothetical protein 
29STMMW_02931328926..329447 [+], 522378443734pathogenicity island protein 
30STMMW_02941329844..332033 [+], 2190378443735putative type VI system protein  TssI
31STMMW_02951332057..332503 [+], 447378443736hypothetical protein 
32STMMW_02961332522..336616 [+], 4095378443737putative Rhs family protein  PAAR
33STMMW_02971336610..336873 [+], 264378443738hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STM0277, SciK, STY2606, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STMMW_02791316864..317349 [+], 486378443722putative hemolysin-coregulated protein SciK
2STMMW_02811317654..318139 [+], 486378443723hypothetical protein STM0277
3STMMW_02841318650..319135 [+], 486378443725putative hemolysin-coregulated protein SciK
4STMMW_239712510581..2510949 [+], 369378445802hypothetical protein STY2606
5STMMW_309113282213..3282698 [-], 486378446482hypothetical protein Hcp

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Proteins        Genes

Homology Immunity protein list
STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STMMW_02831318124..318507 [+], 384378443724hypothetical protein STM0278
2STMMW_239812510949..2511467 [+], 519378445803putative lipoprotein STY2607

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Proteins        Genes