I. Summary
SecReT6 ID552 insolico
StrainSalmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1STM474_0271 (mltD)299914..301281 [-], 1368379699476membrane-bound lytic murein transglycosylase D 
2STM474_0272301353..302108 [-], 756379699477putative periplasmic fimbrial chaperone 
3STM474_0273 (yafS)302143..302865 [+], 723379699478putative SAM-dependent methyltransferase 
4STM474_0274 (rnhA)302862..303329 [-], 468379699479ribonuclease H 
5STM474_0275 (dnaQ)303384..304124 [+], 741379699480DNA polymerase III subunit epsilon 
6STM474_0277304656..305711 [-], 1056379699481putative cytoplasmic protein  TssA
7STM474_0278305722..306717 [-], 996379699482putative cytoplasmic protein  TssG
8STM474_0279 (vasA)306714..308597 [-], 1884379699483type VI secretion protein  TssF
9STM474_0280308613..309107 [-], 495379699484putative cytoplasmic protein  TssE
10STM474_0281 (sciE)309104..309943 [-], 840379699485SciE protein  TagJ
11STM474_0282309915..310817 [-], 903379699486putative cytoplasmic protein 
12STM474_0283311185..313824 [+], 2640379699487putative chaperone ATPase  TssH
13STM474_0284313924..314466 [+], 543379699488putative cytoplasmic protein  TssB
14STM474_0285314490..315983 [+], 1494379699489SciI protein  TssC
15STM474_0286316046..316156 [+], 111379699490invasol SirA 
16STM474_0287316169..316615 [+], 447379699491putative cytoplasmic protein 
17STM474_0288316869..317354 [+], 486379699492hypothetical protein  TssD
18STM474_0289317659..318144 [+], 486379699493putative cytoplasmic protein  STM0277 (e)
19STM474_0290318129..318512 [+], 384379699494hypothetical protein  STM0278 (i)
20STM474_0291318655..319140 [+], 486379699495putative cytoplasmic protein  TssD
21STM474_0292319207..319743 [+], 537379699496putative outer membrane lipoprotein  TssJ
22STM474_0293319747..321090 [+], 1344379699497hypothetical protein  TssK
23STM474_0294321087..322391 [+], 1305379699498Putative outer membrane protein, OmpA family  TssL
24STM474_0295322396..323169 [+], 774379699499putative inner membrane protein 
25STM474_0296 (sciR)323360..323803 [+], 444379699500SciR protein 
26STM474_0297 (sciS)323837..327706 [+], 3870379699501SciS protein  TssM
27STM474_0298327706..328494 [+], 789379699502putative cytoplasmic protein 
28STM474_0299328491..328907 [+], 417379699503hypothetical protein 
29STM474_0300328931..329452 [+], 522379699504putative cytoplasmic protein 
30STM474_0301329849..332038 [+], 2190379699505Rhs-family protein  TssI
31STM474_0302332062..332508 [+], 447379699506hypothetical protein 
32STM474_0303 (rhs1)332521..336123 [+], 3603379699507Rhs1 protein  PAAR
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STM0277, SciK, STY2606, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STM474_0288316869..317354 [+], 486379699492hypothetical protein SciK
2STM474_0289317659..318144 [+], 486379699493putative cytoplasmic protein STM0277
3STM474_0291318655..319140 [+], 486379699495putative cytoplasmic protein SciK
4STM474_24742484631..2484999 [+], 369379701609putative cytoplasmic protein STY2606
5STM474_32803311675..3312160 [-], 486379702388putative cytoplasmic protein Hcp

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Proteins        Genes

Homology Immunity protein list
STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STM474_0290318129..318512 [+], 384379699494hypothetical protein STM0278
2STM474_24752484999..2485517 [+], 519379701610hypothetical protein STY2607

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Proteins        Genes