I. Summary
SecReT6 ID553 insolico
StrainSalmonella enterica subsp. enterica serovar Typhimurium str. T000240
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1STMDT12_C02560 (mltD)299924..301144 [-], 1221378982797membrane-bound lytic murein transglycosylase D 
2STMDT12_C02570301363..302118 [-], 756378982798hydroxyacylglutathione hydrolase 
3STMDT12_C02580302153..302875 [+], 723378982799putative methyltransferase 
4STMDT12_C02590 (rnhA)302872..303339 [-], 468378982800ribonuclease H 
5STMDT12_C02600303394..304134 [+], 741378982801DNA polymerase III subunit epsilon 
6STMDT12_C02610304468..304575 [+], 108378982802hypothetical protein 
7STMDT12_C02620304666..305715 [-], 1050378982803ImpA-related N- family protein  TssA
8STMDT12_C02630305732..306727 [-], 996378982804putative cytoplasmic protein  TssG
9STMDT12_C02640306724..308607 [-], 1884378982805hypothetical protein  TssF
10STMDT12_C02650308623..309117 [-], 495378982806putative cytoplasmic protein  TssE
11STMDT12_C02660309114..309938 [-], 825378982807putative cytoplasmic protein  TagJ
12STMDT12_C02670309925..310827 [-], 903378982808putative cytoplasmic protein 
13STMDT12_C02680311195..313834 [+], 2640378982809putative chaperone ATPase  TssH
14STMDT12_C02690313934..314476 [+], 543378982810type VI secretion protein  TssB
15STMDT12_C02700314500..316008 [+], 1509378982811SciI protein  TssC
16STMDT12_C02710316894..317379 [+], 486378982812hemolysin-coregulated protein  TssD
17STMDT12_C02720317684..318169 [+], 486378982813putative cytoplasmic protein  STM0277 (e)
18STMDT12_C02730318205..318537 [+], 333378982814hypothetical protein  STM0278 (i)
19STMDT12_C02740318680..319165 [+], 486378982815hemolysin-coregulated protein  TssD
20STMDT12_C02750319232..319768 [+], 537378982816putative outer membrane lipoprotein  TssJ
21STMDT12_C02760319772..321115 [+], 1344378982817type VI secretion protein  TssK
22STMDT12_C02770321112..322416 [+], 1305378982818hypothetical protein  TssL
23STMDT12_C02780322421..323194 [+], 774378982819putative inner membrane protein 
24STMDT12_C02790323472..323828 [+], 357378982820putative Shiga-like toxin A subunit 
25STMDT12_C02800323862..327731 [+], 3870378982821putative inner membrane protein  TssM
26STMDT12_C02810327731..328519 [+], 789378982822putative cytoplasmic protein 
27STMDT12_C02820328516..328932 [+], 417378982823hypothetical protein 
28STMDT12_C02830328959..329477 [+], 519378982824pathogenicity island protein 
29STMDT12_C02840329874..332063 [+], 2190378982825putative cytoplasmic protein  TssI
30STMDT12_C02850332087..332533 [+], 447378982826hypothetical protein 
31STMDT12_C02860332552..336646 [+], 4095378982827putative RHS-like protein  PAAR
32STMDT12_C02870336640..336903 [+], 264378982828hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STM0277, SciK, STY2606, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STMDT12_C02710316894..317379 [+], 486378982812hemolysin-coregulated protein SciK
2STMDT12_C02720317684..318169 [+], 486378982813putative cytoplasmic protein STM0277
3STMDT12_C02740318680..319165 [+], 486378982815hemolysin-coregulated protein SciK
4STMDT12_C239702482458..2482826 [+], 369378984938putative cytoplasmic protein STY2606
5STMDT12_C318503314236..3314721 [-], 486378985725putative cytoplasmic protein Hcp

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Proteins        Genes

Homology Immunity protein list
STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STMDT12_C02730318205..318537 [+], 333378982814hypothetical protein STM0278
2STMDT12_C239802482826..2483344 [+], 519378984939putative lipoprotein STY2607

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Proteins        Genes