I. Summary
SecReT6 ID554 insolico
StrainSalmonella enterica subsp. enterica serovar Typhimurium str. UK-1
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1STMUK_0262 (mltD)299911..301278 [-], 1368378987659membrane-bound lytic murein transglycosylase D 
2STMUK_0263 (gloB)301350..302105 [-], 756378987660hydroxyacylglutathione hydrolase 
3STMUK_0264 (yafS)302140..302862 [+], 723378987661putative SAM-dependent methyltransferase 
4STMUK_0265 (rnhA)302859..303326 [-], 468378987662ribonuclease H 
5STMUK_0266 (dnaQ)303390..304121 [+], 732378987663DNA polymerase III subunit epsilon 
6STMUK_0268304654..305709 [-], 1056378987664putative cytoplasmic protein  TssA
7STMUK_0269305720..306715 [-], 996378987665putative cytoplasmic protein  TssG
8STMUK_0270306712..308595 [-], 1884378987666putative cytoplasmic protein  TssF
9STMUK_0271308611..309105 [-], 495378987667putative cytoplasmic protein  TssE
10STMUK_0272309102..309926 [-], 825378987668putative cytoplasmic protein  TagJ
11STMUK_0273309913..310815 [-], 903378987669putative cytoplasmic protein 
12STMUK_0274311183..313822 [+], 2640378987670putative chaperone ATPase  TssH
13STMUK_0275313922..314464 [+], 543378987671putative cytoplasmic protein  TssB
14STMUK_0276314488..315981 [+], 1494378987672putative cytoplasmic protein  TssC
15STMUK_0277316044..316154 [+], 111378987673invasol SirA 
16STMUK_0278316281..316613 [+], 333378987674putative cytoplasmic protein 
17STMUK_0279316867..317352 [+], 486378987675putative cytoplasmic protein  TssD
18STMUK_0280317657..318142 [+], 486378987676putative cytoplasmic protein  STM0277 (e)
19STMUK_0281318127..318510 [+], 384378987677hypothetical protein  STM0278 (i)
20STMUK_0282318653..319138 [+], 486378987678putative cytoplasmic protein  TssD
21STMUK_0283319205..319741 [+], 537378987679putative outer membrane lipoprotein  TssJ
22STMUK_0284319745..321088 [+], 1344378987680putative cytoplasmic protein  TssK
23STMUK_0285321085..322389 [+], 1305378987681hypothetical protein  TssL
24STMUK_0286322394..323167 [+], 774378987682putative inner membrane protein 
25STMUK_0287323370..323801 [+], 432378987683putative Shiga-like toxin A subunit 
26STMUK_0288323835..327704 [+], 3870378987684putative inner membrane protein  TssM
27STMUK_0289327704..328492 [+], 789378987685putative cytoplasmic protein 
28STMUK_0290328489..328905 [+], 417378987686hypothetical protein 
29STMUK_0291328929..329450 [+], 522378987687putative cytoplasmic protein 
30STMUK_0292329847..332036 [+], 2190378987688putative cytoplasmic protein  TssI
31STMUK_0293332060..332506 [+], 447378987689putative cytoplasmic protein 
32STMUK_0294332525..336619 [+], 4095378987690putative RHS-like protein  PAAR
33STMUK_0295336613..336876 [+], 264378987691hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STM0277, SciK, STY2606, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STMUK_0279316867..317352 [+], 486378987675putative cytoplasmic protein SciK
2STMUK_0280317657..318142 [+], 486378987676putative cytoplasmic protein STM0277
3STMUK_0282318653..319138 [+], 486378987678putative cytoplasmic protein SciK
4STMUK_24052486660..2487028 [+], 369378989761putative cytoplasmic protein STY2606
5STMUK_31193256830..3257315 [-], 486378990449putative cytoplasmic protein Hcp

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Proteins        Genes

Homology Immunity protein list
STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1STMUK_0281318127..318510 [+], 384378987677hypothetical protein STM0278
2STMUK_24062487028..2487546 [+], 519378989762hypothetical protein STY2607

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Proteins        Genes