I. Summary

SecReT6 ID	56
Strain	Yersinia pestis biovar Microtus str. 91001
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_005810
Location	1480241..1524047
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YP_1345	1475925..1476245 [+], 321	45441171	hypothetical protein
2	YP_1346 (fabZ1)	1476509..1477033 [+], 525	45441172	myristoyl-acyl carrier dehydratase
3	YP_1347 (fabF3)	1477023..1478306 [+], 1284	45441173	3-ketoacyl-ACP synthase
4	YP_1348 (fabG6)	1478254..1479045 [+], 792	45441174	3-ketoacyl-ACP reductase
5	YP_1349 (pksG)	1479061..1480299 [+], 1239	45441175	hydroxymethylglutaryl-coenzyme A synthase
6	YP_1350 (caiD1)	1480241..1481011 [+], 771	45441176	enoyl-CoA hydratase
7	YP_1351 (caiD2)	1480989..1481765 [+], 777	45441177	polyketide biosynthesis enoyl-CoA hydratase
8	YP_1352 (fabG7)	1481768..1482556 [+], 789	45441178	short chain dehydrogenase
9	YP_1353	1482595..1483083 [+], 489	45441179	hypothetical protein
10	YP_1354 (acpP1)	1483121..1483369 [+], 249	45441180	acyl carrier protein
11	YP_1355 (fabD1)	1483468..1484316 [+], 849	45441181	acyl transferase
12	YP_1356	1485302..1485805 [+], 504	45441182	hypothetical protein	TssB
13	YP_1357	1485848..1487392 [+], 1545	45441183	hypothetical protein	TssC
14	YP_1358	1487404..1488756 [+], 1353	45441184	hypothetical protein	TssK
15	YP_1359	1488753..1489439 [+], 687	45441185	hypothetical protein	TssL
16	YP_1360 (ompA2)	1489439..1491175 [+], 1737	45441186	hypothetical protein	TagL
17	YP_1361 (hcp3)	1491179..1491670 [+], 492	45441187	hemolysin-coregulated protein	TssD
18	YP_1362 (clpA2)	1492058..1494700 [+], 2643	45441188	ATPase subunit of ATP-dependent protease	TssH
19	YP_1363 (vgrG1)	1494703..1497051 [+], 2349	45441189	hypothetical protein	TssI
20	YP_1364	1497067..1499367 [+], 2301	45441190	hypothetical protein
21	YP_1365 (uvrA2)	1499364..1500137 [+], 774	45441191	hypothetical protein
22	YP_1366 (mdlB3)	1500291..1500551 [+], 261	45441192	ABC-type multidrug/protein/lipid transport system, ATPase
23	YP_1367	1500567..1502750 [+], 2184	45441193	hypothetical protein
24	YP_1368	1502923..1503393 [+], 471	45441194	hypothetical protein
25	YP_1369	1504126..1504446 [-], 321	45441195	transposase
26	YP_1370	1505669..1506790 [+], 1122	45441196	hypothetical protein
27	YP_1371 (icmF1)	1506787..1510209 [+], 3423	45441197	hypothetical protein	TssM
28	YP_1373	1511844..1512929 [+], 1086	45441198	hypothetical protein	PAAR
29	YP_1374	1512929..1513399 [+], 471	45441199	hypothetical protein
30	YP_1375	1513620..1515383 [+], 1764	45441200	hypothetical protein	TssF
31	YP_1376	1515347..1516432 [+], 1086	45441201	hypothetical protein	TssG
32	YP_1377	1516407..1516988 [+], 582	45441202	hypothetical protein	TssJ
33	YP_1378	1516988..1517440 [+], 453	45441203	hypothetical protein	TssE
34	YP_1379	1517465..1518832 [+], 1368	45441204	hypothetical protein	TssA
35	YP_1380	1519044..1519667 [-], 624	45441205	hypothetical protein
36	YP_1381 (uup3)	1520182..1521945 [+], 1764	45441206	ABC transporter ATP-binding protein
37	YP_1382	1522173..1522817 [+], 645	45441207	hypothetical protein
38	YP_1383	1522839..1524047 [-], 1209	45441208	transposase for the IS285 insertion element
39	YP_1384 (moeB)	1524214..1525014 [-], 801	45441209	molybdopterin biosynthesis protein MoeB
40	YP_1385 (moeA)	1524986..1526260 [-], 1275	45441210	molybdopterin biosynthesis protein MoeA
41	YP_1386 (aslB1)	1526795..1528105 [-], 1311	45441211	heme-binding protein
42	YP_1387 (phnL3)	1528115..1528783 [-], 669	45441212	ABC transporter ATP-binding protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YP_1361(hcp3)	1491179..1491670 [+], 492	45441187	hemolysin-coregulated protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation