I. Summary
SecReT6 ID560 insolico
StrainSalmonella enterica subsp. enterica serovar Typhimurium str. 798
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1UMN798_0284 (mltD)299912..301132 [-], 1221383495078membrane-bound lytic murein transglycosylase d precursor 
2UMN798_0285 (gloB)301351..302106 [-], 756383495079hydroxyacylglutathione hydrolase 
3UMN798_0286302195..302863 [+], 669383495080hypothetical protein 
4UMN798_0287 (rnhA)302860..303327 [-], 468383495081ribonuclease H 
5UMN798_0288 (dnaQ)303382..304122 [+], 741383495082DNA polymerase III subunit epsilon 
6UMN798_0290 (sciA)304654..305703 [-], 1050383495083SPI-6 associated protein  TssA
7UMN798_0291 (sciB)305720..306715 [-], 996383495084SPI-6 associated protein  TssG
8UMN798_0292 (sciC)306712..308595 [-], 1884383495085SPI-6 associated protein  TssF
9UMN798_0293 (sciD)308611..309105 [-], 495383495086SPI-6 associated protein  TssE
10UMN798_0294 (sciE)309102..309926 [-], 825383495087SPI-6 associated protein  TagJ
11UMN798_0295 (sciF)309913..310815 [-], 903383495088SPI-6 associated protein 
12UMN798_0296 (sciG)311183..313822 [+], 2640383495089SPI-6 associated protein  TssH
13UMN798_0297 (sciH)313922..314464 [+], 543383495090SPI-6 associated protein  TssB
14UMN798_0298 (sciI)314488..315981 [+], 1494383495091SPI-6 associated protein  TssC
15UMN798_0300 (sciK)316867..317352 [+], 486383495092SPI-6 associated protein  TssD
16UMN798_0301317702..318142 [+], 441383495093SPI-6 associated protein  STM0277 (e)
17UMN798_0302318178..318510 [+], 333383495094SPI-6 associated protein  STM0278 (i)
18UMN798_0303 (sciK1)318653..319138 [+], 486383495095SPI-6 associated protein  TssD
19UMN798_0304 (sciN)319250..319741 [+], 492383495096lipoprotein (SPI-6 associated)  TssJ
20UMN798_0305 (sciO)319745..321088 [+], 1344383495097SPI-6 associated protein  TssK
21UMN798_0306 (sciP)321085..322389 [+], 1305383495098membrane protein (SPI-6 associated)  TssL
22UMN798_0307 (sciQ)322394..323167 [+], 774383495099membrane protein, virulence associated protein 
23UMN798_0308 (sciR)323445..323801 [+], 357383495100SPI-6 associated protein 
24UMN798_0309 (sciS)323835..327704 [+], 3870383495101IcmF-related integral membrane ATP-binding protein, virulence associated protein  TssM
25UMN798_0310 (sciT)327719..328492 [+], 774383495102SPI-6 associated protein 
26UMN798_0311 (sciU)328489..328905 [+], 417383495103hypothetical protein 
27UMN798_0312 (sciV)328929..329450 [+], 522383495104SPI-6 associated protein 
28UMN798_0314 (vrgS)329847..332036 [+], 2190383495105type VI secretion protein  TssI
29UMN798_0315 (sciW)332060..332506 [+], 447383495106SPI-6 associated protein 
30UMN798_0316332525..333820 [+], 1296383495107Rhs-family protein (SPI-6 associated)  PAAR
31UMN798_0317333833..336121 [+], 2289383495108Rhs-family protein (SPI-6 associated) 
32UMN798_0318336115..336378 [+], 264383495109hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STM0277, SciK, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1UMN798_0300(sciK)316867..317352 [+], 486383495092SPI-6 associated protein SciK
2UMN798_0301317702..318142 [+], 441383495093SPI-6 associated protein STM0277
3UMN798_0303(sciK1)318653..319138 [+], 486383495095SPI-6 associated protein SciK
4UMN798_34043310777..3311262 [-], 486383497791hypothetical protein Hcp

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Proteins        Genes

Homology Immunity protein list
STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1UMN798_0302318178..318510 [+], 333383495094SPI-6 associated protein STM0278
2UMN798_25632484363..2484881 [+], 519383497076lipoprotein STY2607

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Proteins        Genes