I. Summary
SecReT6 ID58 insolico
StrainYersinia pestis biovar Microtus str. 91001
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YP_34523923357..3924190 [-], 83445443195hypothetical protein 
2YP_3453 (dAP2)3924567..3925943 [-], 137745443196hypothetical protein 
3YP_3454 (yspR)3926511..3927254 [+], 74445443197quorum-sensing transcriptional regulator 
4YP_3455 (yspI)3927235..3927885 [-], 65145443198N-acylhomoserine lactone synthase 
5YP_34563929055..3929705 [+], 65145443199hypothetical protein 
6YP_34573930156..3930551 [+], 39645443200lipoprotein 
7YP_3458 (insA1)3930613..3930882 [+], 27045443201insertion element protein 
8YP_34603931056..3931427 [+], 37245443202hypothetical protein 
9YP_34613932824..3933327 [+], 50445443203hypothetical protein  TssB
10YP_34623933370..3934920 [+], 155145443204hypothetical protein  TssC
11YP_34633934932..3936284 [+], 135345443205hypothetical protein  TssK
12YP_34643936281..3936967 [+], 68745443206hypothetical protein  TssL
13YP_3465 (ompA4)3936967..3938703 [+], 173745443207OmpA family membrane protein  TagL
14YP_3466 (hcp8)3938707..3939198 [+], 49245443208hemolysin-coregulated protein  TssD
15YP_3467 (clpB3)3939616..3942264 [+], 264945443209Clp ATPase  TssH
16YP_3468 (vgrG4)3942261..3944609 [+], 234945443210hypothetical protein  TssI
17YP_34693944624..3946846 [+], 222345443211hypothetical protein 
18YP_34703946847..3947347 [+], 50145443212hypothetical protein 
19YP_34713947531..3947725 [+], 19545443213hypothetical protein 
20YP_34723947751..3948029 [+], 27945443214insertion sequence protein 
21YP_3474 (mdlB7)3948950..3949585 [+], 63645443215ABC-type multidrug/protein/lipid transport system, ATPase 
22YP_34753949601..3951898 [+], 229845443216kinase 
23YP_34763951885..3952652 [+], 76845443217hypothetical protein 
24YP_3477 (insA2)3952745..3953023 [+], 27945443218insertion sequence protein 
25YP_3478 (insB)3953077..3953445 [+], 36945443219insertion sequence protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1YP_3466(hcp8)3938707..3939198 [+], 49245443208hemolysin-coregulated protein EC042_4529

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Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation