I. Summary

SecReT6 ID	58
Strain	Yersinia pestis biovar Microtus str. 91001
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_005810
Location	3927235..3951898
Comment
Function	N/A
T6SS Type	Type i; subtype i2
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	0	1	1	0	0
Component	TssG	TssJ	TssK	TssM
Number	0	0	1	0

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YP_3452	3923357..3924190 [-], 834	45443195	hypothetical protein
2	YP_3453 (dAP2)	3924567..3925943 [-], 1377	45443196	hypothetical protein
3	YP_3454 (yspR)	3926511..3927254 [+], 744	45443197	quorum-sensing transcriptional regulator
4	YP_3455 (yspI)	3927235..3927885 [-], 651	45443198	N-acylhomoserine lactone synthase
5	YP_3456	3929055..3929705 [+], 651	45443199	hypothetical protein
6	YP_3457	3930156..3930551 [+], 396	45443200	lipoprotein
7	YP_3458 (insA1)	3930613..3930882 [+], 270	45443201	insertion element protein
8	YP_3460	3931056..3931427 [+], 372	45443202	hypothetical protein
9	YP_3461	3932824..3933327 [+], 504	45443203	hypothetical protein	TssB
10	YP_3462	3933370..3934920 [+], 1551	45443204	hypothetical protein	TssC
11	YP_3463	3934932..3936284 [+], 1353	45443205	hypothetical protein	TssK
12	YP_3464	3936281..3936967 [+], 687	45443206	hypothetical protein	TssL
13	YP_3465 (ompA4)	3936967..3938703 [+], 1737	45443207	OmpA family membrane protein	TagL
14	YP_3466 (hcp8)	3938707..3939198 [+], 492	45443208	hemolysin-coregulated protein	TssD
15	YP_3467 (clpB3)	3939616..3942264 [+], 2649	45443209	Clp ATPase	TssH
16	YP_3468 (vgrG4)	3942261..3944609 [+], 2349	45443210	hypothetical protein	TssI
17	YP_3469	3944624..3946846 [+], 2223	45443211	hypothetical protein
18	YP_3470	3946847..3947347 [+], 501	45443212	hypothetical protein
19	YP_3471	3947531..3947725 [+], 195	45443213	hypothetical protein
20	YP_3472	3947751..3948029 [+], 279	45443214	insertion sequence protein
21	YP_3474 (mdlB7)	3948950..3949585 [+], 636	45443215	ABC-type multidrug/protein/lipid transport system, ATPase
22	YP_3475	3949601..3951898 [+], 2298	45443216	kinase
23	YP_3476	3951885..3952652 [+], 768	45443217	hypothetical protein
24	YP_3477 (insA2)	3952745..3953023 [+], 279	45443218	insertion sequence protein
25	YP_3478 (insB)	3953077..3953445 [+], 369	45443219	insertion sequence protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

EC042_4529

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YP_3466(hcp8)	3938707..3939198 [+], 492	45443208	hemolysin-coregulated protein	EC042_4529

Download FASTA format files

Proteins        Genes

N/A

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603]

This literature contains bioinformatics investigation