I. Summary

SecReT6 ID	580
Strain	Yersinia pestis A1122
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_017168
Location	547540..571154
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	1	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

13

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	A1122_02485	544003..546909 [+], 2907	384137494	ATP-dependent helicase HepA
2	A1122_02490	546871..547017 [-], 147	384137495	hypothetical protein
3	A1122_02495	547165..547518 [-], 354	384137496	hypothetical protein
4	A1122_02500	547540..550980 [-], 3441	384137497	hypothetical protein	TssM
5	A1122_02505	551042..552652 [-], 1611	384137498	hypothetical protein	TssL
6	A1122_02510	552649..554004 [-], 1356	384137499	hypothetical protein	TssK
7	A1122_02515	554124..554615 [-], 492	384137500	putative lipoprotein	TssJ
8	A1122_02520	554608..554973 [-], 366	384137501	hypothetical protein	PAAR
9	A1122_02525	554979..555596 [-], 618	384137502	hypothetical protein
10	A1122_02530	555589..556692 [-], 1104	384137503	hypothetical protein
11	A1122_02545	558878..559030 [+], 153	384137504	hypothetical protein
12	A1122_02550	558950..561298 [-], 2349	384137505	Rhs element Vgr protein	TssI
13	A1122_02555	561402..563990 [-], 2589	384137506	Clp ATPase	TssH
14	A1122_02560	564008..564991 [-], 984	384137507	hypothetical protein	TssG
15	A1122_02565	564984..566828 [-], 1845	384137508	type VI secretion protein	TssF
16	A1122_02570	566861..567304 [-], 444	384137509	hypothetical protein	TssE
17	A1122_02575	567378..567896 [-], 519	384137510	hypothetical protein	TssD
18	A1122_02580	568059..569570 [-], 1512	384137511	hypothetical protein	TssC
19	A1122_02585	569570..570130 [-], 561	384137512	hypothetical protein	TssB
20	A1122_02590	570141..571154 [-], 1014	384137513	hypothetical protein	TssA
21	A1122_02595	571484..572227 [+], 744	384137514	hypothetical protein
22	A1122_02600	573450..574070 [+], 621	384137515	ribosomal large subunit pseudouridine synthase A
23	A1122_02605 (djlA)	574368..575201 [-], 834	384137516	Dna-J like membrane chaperone protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

YPK_3558 , YPK_3563

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	A1122_02550	558950..561298 [-], 2349	384137505	Rhs element Vgr protein	YPK_3558
2	A1122_02575	567378..567896 [-], 519	384137510	hypothetical protein	YPK_3563

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Proteins        Genes

N/A

N/A