I. Summary

SecReT6 ID	588
Strain	Yersinia pestis biovar Medievalis str. Harbin 35
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_017265
Location	50171..56891
Comment
Function	N/A
T6SS Type	Type i; subtype i1
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	0	1	0	0	0	1	1	1	2
Component	TssG	TssJ	TssK	TssM
Number	0	0	0	0

6

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YPC_0038	45427..45663 [+], 237	384412736	hypothetical protein
2	YPC_0039 (malK)	45667..46776 [+], 1110	384412737	maltose/maltodextrin transport ATP-binding protein
3	YPC_0040 (lamB)	46847..48118 [+], 1272	384412738	maltoporin
4	YPC_0041 (malM)	48359..49270 [+], 912	384412739	maltose operon periplasmic protein
5	YPC_0042	49507..49665 [-], 159	384412740	hypothetical protein
6	YPC_0043	49609..50019 [+], 411	384412741	hypothetical protein
7	YPC_0044	50171..50689 [-], 519	384412742	hypothetical protein	TssD
8	YPC_0045	51213..51710 [+], 498	384412743	hypothetical protein	TssB
9	YPC_0046	51778..53259 [+], 1482	384412744	hypothetical protein	TssC
10	YPC_0047	53266..53706 [+], 441	384412745	hypothetical protein	TssE
11	YPC_0048	53706..54224 [+], 519	384412746	Protein ImpG/VasA	TssF
12	YPC_0049	54238..55260 [+], 1023	384412747	transposase
13	YPC_0050	55257..56039 [+], 783	384412748	transposase
14	YPC_0051	56055..56891 [+], 837	384412749	Protein ImpG/VasA	TssF
15	YPC_0052	56781..57566 [-], 786	384412750	transposase for insertion sequence IS1661
16	YPC_0053	57620..58264 [-], 645	384412751	insertion element IS1661 DNA-binding protein
17	YPC_0054 (glpR)	58328..59086 [-], 759	384412752	DNA-binding transcriptional repressor
18	YPC_0055 (glpG)	59121..59957 [-], 837	384412753	intramembrane serine protease GlpG
19	YPC_0056 (glpE)	59975..60304 [-], 330	384412754	thiosulfate sulfurtransferase

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ABG57132

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YPC_0044	50171..50689 [-], 519	384412742	hypothetical protein	ABG57132

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Proteins        Genes

N/A

N/A