I. Summary
SecReT6 ID59 insolico
StrainYersinia pestis biovar Microtus str. 91001
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YP_3657 (tbpA)4158781..4159773 [+], 99345443389thiamine transporter substrate binding subunit 
2YP_3658 (thiP)4159737..4161356 [+], 162045443390thiamine transporter membrane protein 
3YP_3659 (thiQ)4161343..4162053 [+], 711229220776thiamine transporter ATP-binding subunit 
4YP_3660 (dedA5)4162122..4162889 [-], 76845443392DedA family membrane protein 
5YP_3661 (polB)4163085..4165454 [+], 237045443393DNA polymerase II 
6YP_3662 (hepA)4165915..4168821 [+], 290745443394ATP-dependent helicase HepA 
7YP_36634169077..4169436 [-], 36045443395hypothetical protein 
8YP_3664 (icmF3)4169452..4172946 [-], 349545443396hypothetical protein  TssM
9YP_36654172955..4174592 [-], 163845443397hypothetical protein  TssL
10YP_36664174562..4175935 [-], 137445443398hypothetical protein  TssK
11YP_36674176019..4176510 [-], 49245443399lipoprotein  TssJ
12YP_36684176503..4176868 [-], 36645443400hypothetical protein  PAAR
13YP_36694176874..4177491 [-], 61845443401hypothetical protein 
14YP_36704177484..4178587 [-], 110445443402hypothetical protein 
15YP_36714178613..4180832 [-], 222045443403hypothetical protein 
16YP_3672 (vgrG5)4180845..4183193 [-], 234945443404hypothetical protein  TssI
17YP_3673 (clpB2)4183297..4185900 [-], 260445443405Clp ATPase  TssH
18YP_36744185903..4186925 [-], 102345443406hypothetical protein  TssG
19YP_36754186879..4188723 [-], 184545443407hypothetical protein  TssF
20YP_36764188756..4189199 [-], 44445443408hypothetical protein  TssE
21YP_36774189273..4189791 [-], 51945443409hypothetical protein  TssD
22YP_36784189954..4191465 [-], 151245443410hypothetical protein  TssC
23YP_36794191465..4192025 [-], 56145443411hypothetical protein  TssB
24YP_36804192036..4193049 [-], 101445443412hypothetical protein  TssA
25YP_36814193379..4194122 [+], 74445443413hypothetical protein 
26YP_3682 (rluA3)4195345..4195965 [+], 62145443414ribosomal large subunit pseudouridine synthase A 
27YP_3683 (djlA)4196263..4197096 [-], 83445443415Dna-J like membrane chaperone protein 
28YP_3684 (imp)4197281..4199623 [+], 234345443416organic solvent tolerance protein 
29YP_3685 (surA)4199691..4200995 [+], 130545443417peptidyl-prolyl cis-trans isomerase SurA 
30YP_3686 (pdxA)4200967..4201974 [+], 1008454434184-hydroxythreonine-4-phosphate dehydrogenase 
31YP_3687 (ksgA)4201967..4202785 [+], 81945443419dimethyladenosine transferase 
32YP_3688 (apaG)4202799..4203176 [+], 37845443420ApaG protein 
33YP_3689 (apaH)4203193..4204062 [+], 87045443421diadenosine tetraphosphatase 
34YP_36904204152..4204616 [-], 46545443422hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
YPK_3558 , YPK_3563

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1YP_3672(vgrG5)4180845..4183193 [-], 234945443404hypothetical protein YPK_3558
2YP_36774189273..4189791 [-], 51945443409hypothetical protein YPK_3563

Download FASTA format files
Proteins        Genes
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation