I. Summary

SecReT6 ID	590
Strain	Yersinia pestis biovar Medievalis str. Harbin 35
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_017265
Location	1414132..1450786
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	2	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	2

15

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YPC_1440 (mltB)	1410333..1411427 [+], 1095	384413988	membrane-bound lytic murein transglycosylase B
2	YPC_1441	1411636..1411776 [+], 141	384413989	hypothetical protein
3	YPC_1442	1412693..1413295 [+], 603	384413990	putative luxR-family regulatory protein
4	YPC_1443	1413653..1414135 [-], 483	384413991	hypothetical protein
5	YPC_1444	1414132..1415814 [-], 1683	384413992	putative OMPA family outer membrane porinprecursor	TagL
6	YPC_1445	1415815..1416516 [-], 702	384413993	hypothetical protein
7	YPC_1446	1416513..1417850 [-], 1338	384413994	hypothetical protein
8	YPC_1447	1417890..1418921 [-], 1032	384413995	putative fimbrial protein
9	YPC_1448	1418928..1420109 [-], 1182	384413996	hypothetical protein	TssA
10	YPC_1449	1420208..1421233 [-], 1026	384413997	hypothetical protein	TssG
11	YPC_1450	1421233..1423113 [-], 1881	384413998	hypothetical protein	TssF
12	YPC_1451	1423251..1423349 [-], 99	384413999	hypothetical protein
13	YPC_1452	1423821..1426571 [+], 2751	384414000	ClpB protein	TssH
14	YPC_1453	1426772..1427317 [+], 546	384414001	frimbrial protein
15	YPC_1454	1427474..1428235 [+], 762	384414002	putative pili chaperone protein
16	YPC_1455	1428363..1429913 [+], 1551	384414003	putative outer membrane fimbrial usher porinprecursor
17	YPC_1456	1429935..1431143 [-], 1209	384414004	putative transposase
18	YPC_1457	1431168..1432358 [+], 1191	384414005	putative outer membrane fimbrial usher porinprecursor
19	YPC_1458	1432343..1432951 [+], 609	384414006	fimbrial protein
20	YPC_1459	1433056..1433580 [+], 525	384414007	hypothetical protein	TssB
21	YPC_1460	1433604..1435106 [+], 1503	384414008	hypothetical protein	TssC
22	YPC_1461	1435432..1435917 [+], 486	384414009	hypothetical protein	TssD
23	YPC_1462	1436170..1436730 [+], 561	384414010	putative exported protein precursor	TssJ
24	YPC_1463	1436734..1438083 [+], 1350	384414011	hypothetical protein	TssK
25	YPC_1464	1438116..1438748 [+], 633	384414012	Flagellar motor rotation protein motB	TssL
26	YPC_1465	1438762..1439784 [+], 1023	384414013	transposase
27	YPC_1466	1439781..1440563 [+], 783	384414014	transposase
28	YPC_1467	1440579..1441415 [+], 837	384414015	putative OmpA family protein	TssL
29	YPC_1468	1441402..1441542 [+], 141	384414016	hypothetical protein
30	YPC_1469	1441424..1443829 [+], 2406	384414017	hypothetical protein	TssM
31	YPC_1470	1443835..1445250 [+], 1416	384414018	hypothetical protein	TssM
32	YPC_1471	1445544..1448129 [+], 2586	384414019	hypothetical protein	TssI
33	YPC_1472	1448228..1448488 [+], 261	384414020	hypothetical protein	PAAR
34	YPC_1473	1448488..1449336 [+], 849	384414021	hypothetical protein
35	YPC_1474	1449356..1450162 [+], 807	384414022	Protein of avirulence locus ImpE	TagJ
36	YPC_1475	1450307..1450786 [+], 480	384414023	hypothetical protein	TssE
37	YPC_1476	1450811..1451158 [+], 348	384414024	hypothetical protein
38	YPC_1477	1451233..1451574 [-], 342	384414025	hypothetical protein
39	YPC_1478	1451913..1452020 [-], 108	384414026	hypothetical protein
40	YPC_1479	1451950..1453989 [-], 2040	384414027	hypothetical protein
41	YPC_1480 (lemA)	1453994..1454536 [-], 543	384414028	hypothetical protein
42	YPC_1482	1455106..1455225 [+], 120	384414029	hypothetical protein
43	YPC_1483	1455152..1455619 [+], 468	384414030	hypothetical protein
44	YPC_1484	1455639..1455734 [-], 96	384414031	hypothetical protein

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

ROD_27741

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YPC_1461	1435432..1435917 [+], 486	384414009	hypothetical protein	ROD_27741

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Proteins        Genes

N/A

N/A