I. Summary

SecReT6 ID	592
Strain	Yersinia pestis biovar Medievalis str. Harbin 35
Replicon	chromosome [Browse all T6SS(s) in this replicon]
Accession	NC_017265
Location	3870184..3893796
Comment
Function	N/A
T6SS Type	Type i; subtype i3
Bioinformatics investigation has been performed on this T6SS.

II. T6SS components

Component	TssH	TssD	TssL	TssI	TssA	TssB	TssC	TssE	TssF
Number	1	1	0	1	1	1	1	1	1
Component	TssG	TssJ	TssK	TssM
Number	1	1	1	1

III. genome coordinates of the T6SS gene cluster
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Note
1	YPC_4008 (djlA)	3866137..3866970 [+], 834	384416363	DnaJ-like membrane chaperone protein
2	YPC_4009 (rluA)	3867268..3867888 [-], 621	384416364	Ribosomal large subunit pseudouridine synthase A
3	YPC_4010	3869111..3869854 [-], 744	384416365	hypothetical protein
4	YPC_4011	3870184..3871197 [+], 1014	384416366	hypothetical protein	TssA
5	YPC_4012	3871208..3871768 [+], 561	384416367	hypothetical protein	TssB
6	YPC_4013	3871768..3873279 [+], 1512	384416368	hypothetical protein	TssC
7	YPC_4014	3873442..3873960 [+], 519	384416369	hypothetical protein	TssD
8	YPC_4015	3874034..3874477 [+], 444	384416370	hypothetical protein	TssE
9	YPC_4016	3874510..3876354 [+], 1845	384416371	hypothetical protein	TssF
10	YPC_4017	3876347..3877330 [+], 984	384416372	hypothetical protein	TssG
11	YPC_4018	3877333..3879936 [+], 2604	384416373	ClpB protein	TssH
12	YPC_4019	3880040..3882388 [+], 2349	384416374	hypothetical protein	TssI
13	YPC_4020	3882401..3884620 [+], 2220	384416375	hypothetical protein
14	YPC_4021	3884646..3885749 [+], 1104	384416376	hypothetical protein
15	YPC_4022	3885742..3886359 [+], 618	384416377	hypothetical protein
16	YPC_4023	3886365..3886730 [+], 366	384416378	hypothetical protein	PAAR
17	YPC_4024	3886723..3887214 [+], 492	384416379	putative lipoprotein	TssJ
18	YPC_4025	3887334..3888689 [+], 1356	384416380	hypothetical protein	TssK
19	YPC_4028	3890344..3893796 [+], 3453	384416381	hypothetical protein	TssM
20	YPC_4029	3893818..3894171 [+], 354	384416382	hypothetical protein
21	YPC_4030	3894250..3894465 [+], 216	384416383	hypothetical protein
22	YPC_4031 (hepA)	3894427..3897333 [-], 2907	384416384	ATP-dependent helicase HepA

 Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files

Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.

1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Job_id: Replicon RefSeq: T6SS Region Start (bp): T6SS Region End (bp): Upstream Region (kb): Downstream Region (kb):

Homology Effector list

YPK_3563 , YPK_3558

Effector identified
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Homolog
1	YPC_4014	3873442..3873960 [+], 519	384416369	hypothetical protein	YPK_3563
2	YPC_4019	3880040..3882388 [+], 2349	384416374	hypothetical protein	YPK_3558

Download FASTA format files

Proteins        Genes

N/A

N/A