I. Summary
SecReT6 ID614 insolico
StrainPseudomonas aeruginosa NCGM2.S1
Repliconchromosome I [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1NCGM2_0078 (ppkA)90932..94030 [-], 3099386063051serine/threonine protein kinase  PpkA
2NCGM2_007994038..94766 [-], 729386063052putative phosphoprotein phosphatase  PppA
3NCGM2_008094776..95456 [-], 681386063053hypothetical protein  TagF
4NCGM2_008195453..98986 [-], 3534386063054hypothetical protein  TssM
5NCGM2_008298983..100332 [-], 1350386063055hypothetical protein  TssL
6NCGM2_0083100339..101673 [-], 1335386063056hypothetical protein  TssK
7NCGM2_0084101689..102153 [-], 465386063057putative lipoprotein  TssJ
8NCGM2_0085102198..103721 [-], 1524386063058hypothetical protein  Fha
9NCGM2_0086104089..105123 [+], 1035386063059hypothetical protein  TssA
10NCGM2_0087105212..105730 [+], 519386063060hypothetical protein  TssB
11NCGM2_0088105743..107239 [+], 1497386063061hypothetical protein  TssC
12NCGM2_0089107315..107803 [+], 489386063062hypothetical protein  TssD
13NCGM2_0090108031..108816 [+], 786386063063putative secretion protein  TagJ
14NCGM2_0091108818..109327 [+], 510386063064hypothetical protein  TssE
15NCGM2_0092109324..111183 [+], 1860386063065hypothetical protein  TssF
16NCGM2_0093111147..112193 [+], 1047386063066hypothetical protein  TssG
17NCGM2_0094 (clpB)112186..114894 [+], 2709386063067putative ClpA/B-type chaperone  TssH
18NCGM2_0095114932..116872 [+], 1941386063068hypothetical protein  TssI
19NCGM2_0096116987..117262 [-], 276386063069hypothetical protein  Tsi6 (i)
20NCGM2_0097117284..117517 [-], 234386063070hypothetical protein 
21NCGM2_0098117507..118889 [-], 1383386063071hypothetical protein  Tse6 (e)
22NCGM2_0099118905..119339 [-], 435386063072hypothetical protein 
23NCGM2_0100119593..121818 [+], 2226386063073hypothetical protein  TssI
24NCGM2_0101121846..122295 [+], 450386063074hypothetical protein 
25NCGM2_0102122312..123424 [+], 1113386063075hypothetical protein 
26NCGM2_0103123421..124458 [+], 10383860630763-oxoacyl-(acyl carrier protein) synthase 
27NCGM2_0104124458..125618 [+], 1161386063077hypothetical protein  PA0099 (e)
28NCGM2_0105125640..126560 [+], 921386063078hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PA0085 , PA0091, PA0093, PA0095, PA0099, PA1844, PA2684, PA2685, PA2702, PA2774, PA3484

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NCGM2_0089107315..107803 [+], 489386063062hypothetical protein PA0085
2NCGM2_0095114932..116872 [+], 1941386063068hypothetical protein PA0091
3NCGM2_0098117507..118889 [-], 1383386063071hypothetical protein PA0093
4NCGM2_0100119593..121818 [+], 2226386063073hypothetical protein PA0095
5NCGM2_0104124458..125618 [+], 1161386063077hypothetical protein PA0099
6NCGM2_27592935844..2936308 [-], 465386065692hypothetical protein PA1844
7NCGM2_3711(rhs)4048405..4052358 [-], 3954386066636hypothetical protein PA2684
8NCGM2_37124052408..4054477 [-], 2070386066637hypothetical protein PA2685
9NCGM2_37294073509..4073985 [+], 477386066654hypothetical protein PA2702
10NCGM2_38224166027..4166614 [-], 588386066745hypothetical protein PA2774
11NCGM2_46244979572..4980798 [+], 1227386067528hypothetical protein PA3484

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Proteins        Genes

Homology Immunity protein list
PA0092, PA1845, PA2703, PA2775, PA3485

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NCGM2_0096116987..117262 [-], 276386063069hypothetical protein PA0092
2NCGM2_27602936350..2936868 [-], 519386065693hypothetical protein PA1845
3NCGM2_37304073995..4074228 [+], 234386066655hypothetical protein PA2703
4NCGM2_38234166619..4167056 [-], 438386066746hypothetical protein PA2775
5NCGM2_46254980795..4981232 [+], 438386067529hypothetical protein PA3485

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Proteins        Genes