SecReT6
I. Summary
SecReT6 ID616 insolico
StrainPseudomonas aeruginosa NCGM2.S1
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_017549
Location3605419..3625304
Comment
FunctionN/A
T6SS TypeType i; subtype i4a
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1011
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1NCGM2_3364 (msuC)3600633..3601817 [-], 1185386066293putative FMNH2-dependent monooxygenase 
2NCGM2_3365 (msuD)3601847..3602992 [-], 1146386066294methanesulfonate sulfonatase 
3NCGM2_3366 (msuE)3603002..3603562 [-], 561386066295NADH-dependent FMN reductase 
4NCGM2_33673603722..3603988 [-], 267386066296hypothetical protein 
5NCGM2_33683603965..3604213 [+], 249386066297hypothetical protein 
6NCGM2_3369 (sfnR)3604224..3605309 [-], 1086386066298putative transcriptional regulator  Sfa3
7NCGM2_33703605419..3606519 [-], 1101386066299hypothetical protein  TssA
8NCGM2_33713606516..3610331 [-], 3816386066300hypothetical protein  TssM
9NCGM2_33723610328..3611086 [-], 759386066301hypothetical protein  TssL
10NCGM2_33733611104..3612396 [-], 1293386066302hypothetical protein  TssK
11NCGM2_33743612495..3612971 [-], 477386066303hypothetical protein 
12NCGM2_33753613179..3613724 [+], 546386066304hypothetical protein  TssB
13NCGM2_33763613747..3615231 [+], 1485386066305hypothetical protein  TssC
14NCGM2_33773615305..3615802 [+], 498386066306hypothetical protein  TssD
15NCGM2_33783615815..3616240 [+], 426386066307hypothetical protein  TssE
16NCGM2_33793616224..3618017 [+], 1794386066308hypothetical protein  TssF
17NCGM2_33803617981..3618997 [+], 1017386066309hypothetical protein  TssG
18NCGM2_33813618999..3621548 [+], 2550386066310putative ClpA/B-type protease  TssH
19NCGM2_33823621622..3622155 [+], 534386066311hypothetical protein 
20NCGM2_33833622263..3623261 [+], 999386066312hypothetical protein 
21NCGM2_33843623298..3625304 [+], 2007386066313hypothetical protein  TssI
22NCGM2_33853625315..3625851 [+], 537386066314hypothetical protein 
23NCGM2_33863625874..3626269 [-], 396386066315hypothetical protein 
24NCGM2_33873626546..3627187 [+], 642386066316putative transcriptional regulator 
25NCGM2_33883627388..3628593 [+], 1206386066317hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
PA5089

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NCGM2_0421466750..468987 [+], 2238386063392hypothetical protein PA5089

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Proteins        Genes

Homology Immunity protein list
PA5088, PA5087

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NCGM2_0422469045..469866 [+], 822386063393hypothetical protein PA5088
2NCGM2_0423469923..470744 [+], 822386063394hypothetical protein PA5087

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Proteins        Genes
N/A

Genomics & Bioinformatics Group in MML, SJTU