I. Summary
SecReT6 ID621 insolico
StrainSalmonella enterica subsp. enterica serovar Heidelberg str. B182
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SU5_09031042364..1043584 [-], 1221386590146Membrane-bound lytic murein transglycosylase D 
2SU5_09041043803..1044558 [-], 756386590147Hydroxyacylglutathione hydrolase 
3SU5_09051044593..1045315 [+], 723386590148SAM-dependent methyltransferase 
4SU5_09061045312..1045779 [-], 468386590149Ribonuclease HI 
5SU5_09071045834..1046574 [+], 741386590150DNA polymerase III subunit epsilon 
6SU5_09081047106..1048155 [-], 1050386590151Component of the type VI protein secretion system  TssA
7SU5_09091048172..1049167 [-], 996386590152hypothetical protein  TssG
8SU5_09101049164..1051047 [-], 1884386590153Protein ImpG/VasA  TssF
9SU5_09111051063..1051557 [-], 495386590154hypothetical protein  TssE
10SU5_09121051554..1052378 [-], 825386590155Protein of avirulence locus ImpE  TagJ
11SU5_09131052365..1053255 [-], 891386590156hypothetical protein 
12SU5_09141053635..1056274 [+], 2640386590157ClpB protein  TssH
13SU5_09151056374..1056916 [+], 543386590158hypothetical protein  TssB
14SU5_09161056940..1058448 [+], 1509386590159Type VI protein secretion system  TssC
15SU5_09171058874..1059299 [+], 426386590160putative cytoplasmic protein  STY0301 (i)
16SU5_09181059536..1060021 [+], 486386590161Hemolysin-coregulated protein  TssD
17SU5_09191060324..1060809 [+], 486386590162Type VI secretion system-associated  STM0277 (e)
18SU5_09201060845..1061177 [+], 333386590163type VI secretion system-associated protein  STM0278 (i)
19SU5_09211061320..1061805 [+], 486386590164hemolysin-coregulated protein  TssD
20SU5_09221061918..1062409 [+], 492386590165Type VI secretion lipoprotein/VasD  TssJ
21SU5_09231062413..1063756 [+], 1344386590166Type VI secretion protein  TssK
22SU5_09241063753..1065057 [+], 1305386590167Type VI secretion system OmpA/MotB  TssL
23SU5_09251065224..1065835 [+], 612386590168Putative inner membrane protein 
24SU5_09261066026..1066469 [+], 444386590169SciR Shiga-like toxin A subunit 
25SU5_09271066503..1070372 [+], 3870386590170Type VI secretion protein IcmF  TssM
26SU5_09281070372..1071139 [+], 768386590171type VI secretion system-associated protein 
27SU5_09291071742..1072098 [+], 357386590172hypothetical protein 
28SU5_09301072256..1072642 [+], 387386590173hypothetical protein 
29SU5_09311072669..1073187 [+], 519386590174putative pathogenicity island protein 
30SU5_09321073584..1075815 [+], 2232386590175VgrG protein  TssI
31SU5_09331075875..1076333 [+], 459386590176hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
SciK , STM0277, SciK, STY2606, Hcp

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SU5_09181059536..1060021 [+], 486386590161Hemolysin-coregulated protein SciK
2SU5_09191060324..1060809 [+], 486386590162Type VI secretion system-associated STM0277
3SU5_09211061320..1061805 [+], 486386590164hemolysin-coregulated protein SciK
4SU5_029703219782..3220150 [+], 369386592184NlpC/P60 enzyme STY2606
5SU5_036293971698..3972183 [-], 486386592831hypothetical protein Hcp

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Proteins        Genes

Homology Immunity protein list
STY0301, STM0278, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SU5_09171058874..1059299 [+], 426386590160putative cytoplasmic protein STY0301
2SU5_09201060845..1061177 [+], 333386590163type VI secretion system-associated protein STM0278
3SU5_029713220150..3220668 [+], 519386592185Putative lipoprotein STY2607

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Proteins        Genes