I. Summary
SecReT6 ID623 insolico
StrainEscherichia coli IHE3034
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECOK1_3186 (csdA)3250894..3252099 [+], 1206386600803cysteine desulfurase, catalytic subunit CsdA 
2ECOK1_3187 (csdE)3252099..3252542 [+], 444386600804cysteine desulfuration protein CsdE 
3ECOK1_31883252593..3253399 [-], 807386600805ThiF family protein 
4ECOK1_3189 (mltA)3253476..3254573 [-], 1098386600806membrane-bound lytic murein transglycosylase A 
5ECOK1_31933255714..3256214 [+], 501386600807hypothetical protein  TssB
6ECOK1_31943256273..3257811 [+], 1539386600808hypothetical protein  TssC
7ECOK1_31953257829..3259166 [+], 1338386600809hypothetical protein  TssK
8ECOK1_31963259163..3259828 [+], 666386600810type IV/VI secretion system protein, DotU family  TssL
9ECOK1_31973259841..3261493 [+], 1653386600811OmpA domain-containing protein  TagL
10ECOK1_31983261551..3262042 [+], 492386600812hypothetical protein  TssD
11ECOK1_31993262234..3264879 [+], 2646386600813ClpA/ClpB family protein  TssH
12ECOK1_32003264891..3267371 [+], 2481386600814ImpA family type VI secretion-associated protein  TssI
13ECOK1_32013267391..3269160 [+], 1770386600815hypothetical protein  Tle4 (e)
14ECOK1_32033270992..3272092 [+], 1101386600816hypothetical protein 
15ECOK1_32043272102..3275455 [+], 3354386600817hypothetical protein  TssM
16ECOK1_32053275433..3277058 [+], 1626386600818ImpA-like protein  TssA
17ECOK1_32063277058..3278641 [+], 1584386600819hypothetical protein  PAAR
18ECOK1_32073278641..3279270 [+], 630386600820hypothetical protein 
19ECOK1_32083279336..3279476 [+], 141386600821hypothetical protein 
20ECOK1_32093279785..3279970 [+], 186386600822hypothetical protein 
21ECOK1_3210 (vasA)3280340..3282100 [+], 1761386600823type VI secretion protein  TssF
22ECOK1_32113282064..3283143 [+], 1080386600824type VI secretion protein  TssG
23ECOK1_32123283124..3283660 [+], 537386600825type VI secretion lipoprotein  TssJ
24ECOK1_32133283664..3284092 [+], 429386600826type VI secretion system lysozyme-like protein  TssE
25ECOK1_32143284092..3285468 [+], 1377386600827ImpA domain-containing protein  TssA
26ECOK1_32153285770..3286717 [-], 948386600828D-isomer specific 2-hydroxyacid dehydrogenase family protein 
27ECOK1_32163286789..3287385 [-], 597386600829phosphosugar isomerase 
28ECOK1_32173287388..3288563 [-], 1176386600830class I and II aminotransferase 
29ECOK1_32183288563..3290143 [-], 1581386600831PTS system transporter subunit IIBC 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
EC042_4529 , AHW84487

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECOK1_31983261551..3262042 [+], 492386600812hypothetical protein EC042_4529
2ECOK1_32013267391..3269160 [+], 1770386600815hypothetical protein AHW84487

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Proteins        Genes