I. Summary
SecReT6 ID625 insolico
StrainEscherichia coli UM146
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1UM146_02355505337..506917 [+], 1581386603108Phosphotransferase system system, maltose and glucose-specific IIABC component 
2UM146_02370508094..508690 [+], 597386603109putative phosphosugar isomerase 
3UM146_02375508762..509709 [+], 9483866031102-hydroxyacid dehydrogenase 
4UM146_02380510011..511387 [-], 1377386603111hypothetical protein  TssA
5UM146_02385511387..511815 [-], 429386603112hypothetical protein  TssE
6UM146_02390511819..512355 [-], 537386603113hypothetical protein  TssJ
7UM146_02395512336..513415 [-], 1080386603114hypothetical protein  TssG
8UM146_02400513379..515139 [-], 1761386603115type VI secretion protein  TssF
9UM146_02405515509..515952 [-], 444386603116hypothetical protein 
10UM146_02410516003..516143 [-], 141386603117hypothetical protein 
11UM146_02415516209..516838 [-], 630386603118hypothetical protein 
12UM146_02420516838..518421 [-], 1584386603119hypothetical protein  PAAR
13UM146_02425518421..520058 [-], 1638386603120hypothetical protein  TssA
14UM146_02430520024..523377 [-], 3354386603121hypothetical protein  TssM
15UM146_02435523387..524604 [-], 1218386603122hypothetical protein 
16UM146_02440524525..524785 [-], 261386603123hypothetical protein  PAAR
17UM146_02455526319..528088 [-], 1770386603124hypothetical protein  Tle4 (e)
18UM146_02460528108..530588 [-], 2481386603125hypothetical protein  TssI
19UM146_02465530600..533245 [-], 2646386603126ATPase  TssH
20UM146_02470533437..533928 [-], 492386603127hypothetical protein  TssD
21UM146_02475533986..535638 [-], 1653386603128hypothetical protein  TagL
22UM146_02480535651..536316 [-], 666386603129DotU family type IV / VI secretion system protein  TssL
23UM146_02485536313..537650 [-], 1338386603130hypothetical protein  TssK
24UM146_02490537668..539206 [-], 1539386603131hypothetical protein  TssC
25UM146_02495539265..539765 [-], 501386603132hypothetical protein  TssB
26UM146_02500 (mltA)540907..542004 [+], 1098386603133murein transglycosylase A 
27UM146_02505542081..542887 [+], 807386603134hypothetical protein 
28UM146_02510542938..543381 [-], 444386603135putative Fe-S metabolism protein (sufE-like) 
29UM146_02515543381..544586 [-], 1206386603136cysteine sulfinate desulfinase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
AHW84487 , EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1UM146_02455526319..528088 [-], 1770386603124hypothetical protein AHW84487
2UM146_02470533437..533928 [-], 492386603127hypothetical protein EC042_4529

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Proteins        Genes