I. Summary
SecReT6 ID628 insolico
StrainEscherichia coli O83:H1 str. NRG 857C
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1NRG857_137652895925..2897130 [+], 1206387618077cysteine sulfinate desulfinase 
2NRG857_137702897130..2897573 [+], 444387618078putative Fe-S metabolism protein (sufE-like) 
3NRG857_137752897624..2898430 [-], 807387618079hypothetical protein 
4NRG857_13780 (mltA)2898507..2899604 [-], 1098387618080murein transglycosylase A 
5NRG857_137852900629..2901129 [+], 501387618081hypothetical protein  TssB
6NRG857_137902901188..2902726 [+], 1539387618082hypothetical protein  TssC
7NRG857_137952902746..2904083 [+], 1338387618083hypothetical protein  TssK
8NRG857_138002904080..2904745 [+], 666387618084hypothetical protein  TssL
9NRG857_138052904758..2906410 [+], 1653387618085hypothetical protein  TagL
10NRG857_138102906468..2906959 [+], 492387618086hemolysin-coregulated protein Hcp  TssD
11NRG857_138152907151..2909787 [+], 2637387618087putative CLPA/B-type chaperone protein  TssH
12NRG857_138202909799..2912261 [+], 2463387618088putative VGR-like protein  TssI
13NRG857_138252912276..2913100 [+], 825387618089hypothetical protein 
14NRG857_138302913097..2915073 [+], 1977387618090hypothetical protein 
15NRG857_138352915095..2915355 [+], 261387618091hypothetical protein  PAAR
16NRG857_138402915355..2916788 [+], 1434387618092hypothetical protein 
17NRG857_138452916795..2920133 [+], 3339387618093hypothetical protein  TssM
18NRG857_138502920099..2921736 [+], 1638387618094hypothetical protein  TssA
19NRG857_138552921742..2922992 [+], 1251387618095hypothetical protein  PAAR
20NRG857_138602922995..2923438 [+], 444387618096hypothetical protein 
21NRG857_138652923808..2925568 [+], 1761387618097hypothetical protein  TssF
22NRG857_138702925532..2926611 [+], 1080387618098hypothetical protein  TssG
23NRG857_138752926592..2927128 [+], 537387618099hypothetical protein  TssJ
24NRG857_138802927132..2927560 [+], 429387618100hypothetical protein  TssE
25NRG857_138852927560..2928936 [+], 1377387618101hypothetical protein  TssA
26NRG857_138902929236..2930183 [-], 9483876181022-hydroxyacid dehydrogenase 
27NRG857_138952930255..2930851 [-], 597387618103putative phosphosugar isomerase 
28NRG857_139002930854..2932029 [-], 1176387618104putative aminotransferase 
29NRG857_139052932029..2933609 [-], 1581387618105Phosphotransferase system system, maltose and glucose-specific IIABC component 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NRG857_138102906468..2906959 [+], 492387618086hemolysin-coregulated protein Hcp EC042_4529

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Proteins        Genes