I. Summary
SecReT6 ID629 insolico
StrainEscherichia coli W
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECW_m0210 (yafS)235508..236230 [+], 723386607509putative S-adenosyl-L-methionine-dependent methyltransferase 
2ECW_m0211 (rnhA)236227..236694 [-], 468386607510ribonuclease HI, degrades RNA of DNA-RNA hybrids 
3ECW_m0212 (dnaQ)236750..237490 [+], 741386607511DNA polymerase III subunit epsilon 
4ECW_m0214 (yafT)238030..238815 [+], 786386607512aminopeptidase 
5ECW_m0215 (ykfM)238952..239431 [-], 480386607513hypothetical protein 
6ECW_m0216 (yafU)239441..240355 [-], 915386607514inner membrane protein 
7ECW_m0217 (etsH2)240399..240881 [-], 483386607515Hcp-related protein  TssD
8ECW_m0218 (etsA2)240905..242257 [-], 1353386607516T6SS-associated protein  TssA
9ECW_m0219 (etsI)242268..245792 [-], 3525386607517IcmF-like protein  TssM
10ECW_m0220 (etsA)245811..247223 [-], 1413386607518ImpA domain-containing protein  TssA
11ECW_m0221 (etsX)247228..247971 [-], 744386607519T6SS-associated protein 
12ECW_m0222 (etsV)247968..250775 [-], 2808386607520ClpV ATPase  TssH
13ECW_m0223 (etsU)250784..251545 [-], 762386607521T6SS-associated protein  TssL
14ECW_m0224 (etsM)251550..252881 [-], 1332386607522T6SS-associated protein  TssK
15ECW_m0225 (etsN)252884..253408 [-], 525386607523OM lipoprotein  TssJ
16ECW_m0226 (etsH)253405..254685 [-], 1281386607524forkhead-associated protein  Fha
17ECW_m0227 (etsR)254710..255792 [-], 1083386607525T6SS-associated protein  TssG
18ECW_m0228 (etsC)255756..257606 [-], 1851386607526T6SS-associated protein  TssF
19ECW_m0229 (etsD)257610..258023 [-], 414386607527T6SS-associated protein  TssE
20ECW_m0230 (etsB)258030..259505 [-], 1476386607528T6SS-associated protein  TssC
21ECW_m0231259556..259780 [-], 225386607529hypothetical protein  TssC
22ECW_m0232 (etsS)259815..260315 [-], 501386607530T6SS-associated protein  TssB
23ECW_m0233 (etsH1)261013..261531 [+], 519386607531Hcp-related protein  TssD
24ECW_m0234 (etsG)261741..263882 [+], 2142386607532protein VgrG  TssI
25ECW_m0235 (rhsW1)263958..268007 [+], 4050386607533Type I RHS protein  PAAR
26ECW_m0236267967..268404 [+], 438386607534hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECW_m0233(etsH1)261013..261531 [+], 519386607531Hcp-related protein ABG57132

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Proteins        Genes