I. Summary
SecReT6 ID630 insolico
StrainEscherichia coli W
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECW_m3021 (csdA)3096575..3097780 [+], 1206386610174cysteine sulfinate desulfinase 
2ECW_m3022 (csdE)3097780..3098223 [+], 444386610175Fe-S metabolism protein 
3ECW_m3023 (ygdL)3098274..3099080 [-], 807386610176hypothetical protein 
4ECW_m3024 (mltA)3099157..3100254 [-], 1098386610177membrane-bound lytic murein transglycosylase A 
5ECW_m30283101394..3101894 [+], 501386610178hypothetical protein  TssB
6ECW_m30293101953..3103491 [+], 1539386610179hypothetical protein  TssC
7ECW_m30303103509..3104846 [+], 1338386610180hypothetical protein  TssK
8ECW_m30313104843..3105508 [+], 666386610181Type IV/VI secretion system protein, DotU family  TssL
9ECW_m30323105521..3107173 [+], 1653386610182Putative outer membrane protein/OmpA domain protein  TagL
10ECW_m30333107231..3107722 [+], 492386610183Secreted protein Hcp  TssD
11ECW_m30343107913..3110558 [+], 2646386610184ClpA/ClpB family protein  TssH
12ECW_m30353110570..3113056 [+], 2487386610185ImpA family type VI secretion-associated protein  TssI
13ECW_m30363113058..3113909 [+], 852386610186hypothetical protein 
14ECW_m30373113899..3114435 [+], 537386610187hypothetical protein 
15ECW_m30393117469..3117891 [+], 423386610188hypothetical protein 
16ECW_m30403117893..3118444 [+], 552386610189hypothetical protein 
17ECW_m30413118522..3119736 [+], 1215386610190hypothetical protein 
18ECW_m30423119688..3123125 [+], 3438386610191hypothetical protein  TssM
19ECW_m30443124732..3125649 [+], 918386610192Paar  PAAR
20ECW_m30453126099..3126206 [+], 108386610193hypothetical protein 
21ECW_m30463126751..3128109 [+], 1359386610194type VI secretion-associated protein, family  TssA
22ECW_m30473128115..3128591 [+], 477386610195hypothetical protein  PAAR
23ECW_m30483128584..3129261 [-], 678386610196IS911 transposase ORF2 
24ECW_m30503129450..3129761 [-], 312386610197IS911 transposase ORF1 
25ECW_m30513129823..3130116 [+], 294386610198hypothetical protein 
26ECW_m30523130787..3131209 [+], 423386610199hypothetical protein 
27ECW_m30533131769..3133529 [+], 1761386610200hypothetical protein  TssF
28ECW_m30543133493..3134572 [+], 1080386610201hypothetical protein  TssG
29ECW_m30553134553..3135089 [+], 537386610202type VI secretion lipoprotein  TssJ
30ECW_m30563135093..3135521 [+], 429386610203hypothetical protein  TssE
31ECW_m30573135521..3136897 [+], 1377386610204hypothetical protein  TssA
32ECW_m30583136962..3137510 [+], 549386610205hypothetical protein 
33ECW_m3059 (amiC)3137856..3139109 [-], 1254386610206N-acetylmuramoyl-L-alanine amidase 
34ECW_m3060 (argA)3139341..3140672 [+], 1332386610207fused acetylglutamate kinase-like protein (inactive)/amino acid N-acetyltransferase 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECW_m30333107231..3107722 [+], 492386610183Secreted protein Hcp EC042_4529

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Proteins        Genes